The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis
Aims and objective: The main aim of this study was to employ non-invasive methodologies, such as evaluating the portal vein diameter (PVD) and the size of the spleen, as well as the ratio of platelet count to splenic length, in order to identify individuals with cirrhosis who are at a heightened ris...
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| Format: | Article |
| Language: | English |
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National Board of Examinations
2023-11-01
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| Series: | National Board of Examinations Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://natboard.edu.in/ejournal/articledtl?x=eE9ZV1M3aXFDcFBnNENuZUNIVW5SZz09 |
| _version_ | 1797633911781588992 |
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| author | Priyesh Patel Jignesh Rathod Ravi K Bhatt Kaushik Bhattacharya Ajit kumar Shrivastava Premaram Chaoudhary Vipul D Yagnik |
| author_facet | Priyesh Patel Jignesh Rathod Ravi K Bhatt Kaushik Bhattacharya Ajit kumar Shrivastava Premaram Chaoudhary Vipul D Yagnik |
| author_sort | Priyesh Patel |
| collection | DOAJ |
| description | Aims and objective: The main aim of this study was to employ non-invasive methodologies, such as evaluating the portal vein diameter (PVD) and the size of the spleen, as well as the ratio of platelet count to splenic length, in order to identify individuals with cirrhosis who are at a heightened risk of developing esophageal varices. Materials and Methods: The present study utilized a descriptive analysis methodology to investigate a cohort of 50 individuals who received a diagnosis of liver cirrhosis. The individuals, ranging in age from 35 to 70 years, were subjected to both ultrasonography and upper gastrointestinal endoscopy. The statistical analysis was performed utilizing the one-way analysis of variance (ANOVA) and chi-square tests within the Stata 14 software. Results: In the sample of 50 patients, it was shown that 23 individuals (46%) demonstrated a PVD greater than 12mm. Additionally, a statistically significant correlation was observed between an increase in PVD and a rise in variceal grading. Additionally, it was noted that a total of 31 individuals, including 62% of the sample, displayed a splenic size above 13 cm. Nevertheless, no statistically significant positive connection was observed between the increase in splenic size and the grading of varices. The positive predictive value of a platelet count/spleen length ratio less than 909 is 100%. Conclusion: The application of ultrasound-guided measurement of PVD exceeding 12.0 mm and splenic size exceeding 13.0 cm can be considered a dependable and independent approach for predicting the presence of varices in persons with a diagnosis of cirrhosis. The reliability of predicting esophageal varices is higher when using the platelet count/spleen length ratio of less than 909, as opposed to relying solely on spleen size. However, in cases where there has been no previous instance of gastrointestinal bleeding, it is recommended to consider the use of surveillance endoscopy if any of these predictors are identified in individuals with cirrhosis. |
| first_indexed | 2024-03-11T12:00:19Z |
| format | Article |
| id | doaj.art-02576547353e4998a70536b55b58ee1b |
| institution | Directory Open Access Journal |
| issn | 2583-7524 |
| language | English |
| last_indexed | 2024-03-11T12:00:19Z |
| publishDate | 2023-11-01 |
| publisher | National Board of Examinations |
| record_format | Article |
| series | National Board of Examinations Journal of Medical Sciences |
| spelling | doaj.art-02576547353e4998a70536b55b58ee1b2023-11-08T06:05:29ZengNational Board of ExaminationsNational Board of Examinations Journal of Medical Sciences2583-75242023-11-01Volume 11165866910.61770/NBEJMS.2023.v01.i11.005The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver CirrhosisPriyesh Patel0Jignesh Rathod1Ravi K Bhatt2Kaushik Bhattacharya3Ajit kumar Shrivastava4Premaram Chaoudhary5Vipul D Yagnik6Department of Surgery, Pramukhswami Medical College, Karamsad, Anand, IndiaDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, IndiaDepartment of Surgery, Pramukhswami Medical College, Karamsad, Anand, IndiaDepartment of Surgery, MGM Medical College and LSK Hospital, Kishanganj 855107, Bihar India Department of Paediatrics, Banas Medical College and Research Institute, Palanpur, Gujarat, IndiaDepartment of Physiology, Banas Medical College and Research Institute, Palanpur, Gujarat, IndiaDepartment of Surgery, Banas Medical College and Research Institute, Palanpur, Gujarat, IndiaAims and objective: The main aim of this study was to employ non-invasive methodologies, such as evaluating the portal vein diameter (PVD) and the size of the spleen, as well as the ratio of platelet count to splenic length, in order to identify individuals with cirrhosis who are at a heightened risk of developing esophageal varices. Materials and Methods: The present study utilized a descriptive analysis methodology to investigate a cohort of 50 individuals who received a diagnosis of liver cirrhosis. The individuals, ranging in age from 35 to 70 years, were subjected to both ultrasonography and upper gastrointestinal endoscopy. The statistical analysis was performed utilizing the one-way analysis of variance (ANOVA) and chi-square tests within the Stata 14 software. Results: In the sample of 50 patients, it was shown that 23 individuals (46%) demonstrated a PVD greater than 12mm. Additionally, a statistically significant correlation was observed between an increase in PVD and a rise in variceal grading. Additionally, it was noted that a total of 31 individuals, including 62% of the sample, displayed a splenic size above 13 cm. Nevertheless, no statistically significant positive connection was observed between the increase in splenic size and the grading of varices. The positive predictive value of a platelet count/spleen length ratio less than 909 is 100%. Conclusion: The application of ultrasound-guided measurement of PVD exceeding 12.0 mm and splenic size exceeding 13.0 cm can be considered a dependable and independent approach for predicting the presence of varices in persons with a diagnosis of cirrhosis. The reliability of predicting esophageal varices is higher when using the platelet count/spleen length ratio of less than 909, as opposed to relying solely on spleen size. However, in cases where there has been no previous instance of gastrointestinal bleeding, it is recommended to consider the use of surveillance endoscopy if any of these predictors are identified in individuals with cirrhosis.https://natboard.edu.in/ejournal/articledtl?x=eE9ZV1M3aXFDcFBnNENuZUNIVW5SZz09cirrhosisesophageal varicesportal veinendoscopyultrasonography |
| spellingShingle | Priyesh Patel Jignesh Rathod Ravi K Bhatt Kaushik Bhattacharya Ajit kumar Shrivastava Premaram Chaoudhary Vipul D Yagnik The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis National Board of Examinations Journal of Medical Sciences cirrhosis esophageal varices portal vein endoscopy ultrasonography |
| title | The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis |
| title_full | The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis |
| title_fullStr | The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis |
| title_full_unstemmed | The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis |
| title_short | The Correlation between Portal Vein Diameter, Splenic Size, platelet count/spleen length ratio, and Gastro-Esophageal Varices in the Liver Cirrhosis |
| title_sort | correlation between portal vein diameter splenic size platelet count spleen length ratio and gastro esophageal varices in the liver cirrhosis |
| topic | cirrhosis esophageal varices portal vein endoscopy ultrasonography |
| url | https://natboard.edu.in/ejournal/articledtl?x=eE9ZV1M3aXFDcFBnNENuZUNIVW5SZz09 |
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