Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome

The associations or relationship of MetS and its components with thyroid gland (TG) dysfunction are well known, and the study was aimed at establishing the clinical and functional features of the thyroid gland dysfunction combined with the metabolic syndrome. The study included 90 patients aged 18 y...

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Bibliographic Details
Main Authors: A. A. Fateevа, N. A. Martirosyan, N. A. Petunina
Format: Article
Language:Russian
Published: Remedium Group LLC 2018-03-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2340
Description
Summary:The associations or relationship of MetS and its components with thyroid gland (TG) dysfunction are well known, and the study was aimed at establishing the clinical and functional features of the thyroid gland dysfunction combined with the metabolic syndrome. The study included 90 patients aged 18 years and older with the presence of comorbidities which included metabolic syndrome and thyroid diseases (MetS and TG); with MetS without TG dysfunction and with TG dysfunction without MetS. A comparative assessment of BMI, insulin, HOMA-IR index, lipid profile values was carried out in the studied subgroups of patients depending on the functional state of the thyroid gland. The study showed that the comorbid course of subcompensated hypothyroidism and MetS is associated with aggravation of hyperinsulinemia and insulin resistance, with a tendency towards an increase in BMI, an unfavourable shift in lipid metabolism.
ISSN:2079-701X
2658-5790