Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome

The associations or relationship of MetS and its components with thyroid gland (TG) dysfunction are well known, and the study was aimed at establishing the clinical and functional features of the thyroid gland dysfunction combined with the metabolic syndrome. The study included 90 patients aged 18 y...

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Main Authors: A. A. Fateevа, N. A. Martirosyan, N. A. Petunina
Format: Article
Language:Russian
Published: Remedium Group LLC 2018-03-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2340
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author A. A. Fateevа
N. A. Martirosyan
N. A. Petunina
author_facet A. A. Fateevа
N. A. Martirosyan
N. A. Petunina
author_sort A. A. Fateevа
collection DOAJ
description The associations or relationship of MetS and its components with thyroid gland (TG) dysfunction are well known, and the study was aimed at establishing the clinical and functional features of the thyroid gland dysfunction combined with the metabolic syndrome. The study included 90 patients aged 18 years and older with the presence of comorbidities which included metabolic syndrome and thyroid diseases (MetS and TG); with MetS without TG dysfunction and with TG dysfunction without MetS. A comparative assessment of BMI, insulin, HOMA-IR index, lipid profile values was carried out in the studied subgroups of patients depending on the functional state of the thyroid gland. The study showed that the comorbid course of subcompensated hypothyroidism and MetS is associated with aggravation of hyperinsulinemia and insulin resistance, with a tendency towards an increase in BMI, an unfavourable shift in lipid metabolism.
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spelling doaj.art-026040eae3574267a1550cdda3dabd202023-04-23T06:56:50ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902018-03-010410010410.21518/2079-701X-2018-4-100-1042316Clinical and functional features of thyroid gland dysfunction combined with metabolic syndromeA. A. Fateevа0N. A. Martirosyan1N. A. Petunina2Sechenov First Moscow State Medical University of the Ministry of Health of Russia; Asfendiyarov Kazakh National Medical UniversitySechenov First Moscow State Medical University of the Ministry of Health of RussiaSechenov First Moscow State Medical University of the Ministry of Health of RussiaThe associations or relationship of MetS and its components with thyroid gland (TG) dysfunction are well known, and the study was aimed at establishing the clinical and functional features of the thyroid gland dysfunction combined with the metabolic syndrome. The study included 90 patients aged 18 years and older with the presence of comorbidities which included metabolic syndrome and thyroid diseases (MetS and TG); with MetS without TG dysfunction and with TG dysfunction without MetS. A comparative assessment of BMI, insulin, HOMA-IR index, lipid profile values was carried out in the studied subgroups of patients depending on the functional state of the thyroid gland. The study showed that the comorbid course of subcompensated hypothyroidism and MetS is associated with aggravation of hyperinsulinemia and insulin resistance, with a tendency towards an increase in BMI, an unfavourable shift in lipid metabolism.https://www.med-sovet.pro/jour/article/view/2340metabolic syndromethyroid diseasecomorbid coursecardiovascular complications
spellingShingle A. A. Fateevа
N. A. Martirosyan
N. A. Petunina
Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
Медицинский совет
metabolic syndrome
thyroid disease
comorbid course
cardiovascular complications
title Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
title_full Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
title_fullStr Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
title_full_unstemmed Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
title_short Clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
title_sort clinical and functional features of thyroid gland dysfunction combined with metabolic syndrome
topic metabolic syndrome
thyroid disease
comorbid course
cardiovascular complications
url https://www.med-sovet.pro/jour/article/view/2340
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