NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Patients with head and neck squamous cell carcinoma diagnosed with recurrent tumor or distant metastases usually have the worst prognosis. Chemotherapeutic options are very limited in these patients; there is a probability of drug resistance development. The researchers continue to search more effec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2017-06-01
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| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/271 |
| _version_ | 1826558191140339712 |
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| author | A. M. Mudunov M. N. Narimanov D. A. Safarov |
| author_facet | A. M. Mudunov M. N. Narimanov D. A. Safarov |
| author_sort | A. M. Mudunov |
| collection | DOAJ |
| description | Patients with head and neck squamous cell carcinoma diagnosed with recurrent tumor or distant metastases usually have the worst prognosis. Chemotherapeutic options are very limited in these patients; there is a probability of drug resistance development. The researchers continue to search more effective and less toxic drugs. In the current article, we analyze the results of the latest randomized clinical trials devoted the assessment of novel antitumor immunotherapeutic drugs – PD-1 inhibitors – in patients with head and neck squamous cell carcinoma. This studies reveal new possibilities for the treatment of these patients. |
| first_indexed | 2024-04-10T01:59:19Z |
| format | Article |
| id | doaj.art-02639002e0774a48a1ea4ea27a5424fc |
| institution | Directory Open Access Journal |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| last_indexed | 2025-03-14T08:40:34Z |
| publishDate | 2017-06-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj.art-02639002e0774a48a1ea4ea27a5424fc2025-03-02T12:53:49ZrusABV-pressОпухоли головы и шеи2222-14682411-46342017-06-01729910510.17650/2222-1468-2017-7-2-99-105252NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECKA. M. Mudunov0M. N. Narimanov1D. A. Safarov2N.N. Blokhin Russian Cancer Research Center, Ministry of Health of RussiaN.N. Blokhin Russian Cancer Research Center, Ministry of Health of RussiaN.N. Blokhin Russian Cancer Research Center, Ministry of Health of RussiaPatients with head and neck squamous cell carcinoma diagnosed with recurrent tumor or distant metastases usually have the worst prognosis. Chemotherapeutic options are very limited in these patients; there is a probability of drug resistance development. The researchers continue to search more effective and less toxic drugs. In the current article, we analyze the results of the latest randomized clinical trials devoted the assessment of novel antitumor immunotherapeutic drugs – PD-1 inhibitors – in patients with head and neck squamous cell carcinoma. This studies reveal new possibilities for the treatment of these patients.https://ogsh.abvpress.ru/jour/article/view/271head and neck tumorssquamous cell carcinomapd-1immune therapynivolumabpembrolizumab |
| spellingShingle | A. M. Mudunov M. N. Narimanov D. A. Safarov NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK Опухоли головы и шеи head and neck tumors squamous cell carcinoma pd-1 immune therapy nivolumab pembrolizumab |
| title | NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK |
| title_full | NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK |
| title_fullStr | NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK |
| title_full_unstemmed | NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK |
| title_short | NEW OPPORTUNITIES FOR IMMUNE THERAPY IN PATIENTS WITH DISSEMINATED RECURRENT SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK |
| title_sort | new opportunities for immune therapy in patients with disseminated recurrent squamous cell carcinoma of the head and neck |
| topic | head and neck tumors squamous cell carcinoma pd-1 immune therapy nivolumab pembrolizumab |
| url | https://ogsh.abvpress.ru/jour/article/view/271 |
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