Role of immunohistochemistry in diagnosis of a rare bladder tumor

Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary ne...

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Main Authors: Manjari Kishore, Purnima Malhotra, Minakshi Bhardwaj
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2019-01-01
Series:Journal of Laboratory Physicians
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18
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author Manjari Kishore
Purnima Malhotra
Minakshi Bhardwaj
author_facet Manjari Kishore
Purnima Malhotra
Minakshi Bhardwaj
author_sort Manjari Kishore
collection DOAJ
description Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.
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spelling doaj.art-02640a23ac43442fb082f84038359e712022-12-22T00:03:32ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262019-01-01110109109310.4103/JLP.JLP_119_18Role of immunohistochemistry in diagnosis of a rare bladder tumorManjari Kishore0Purnima Malhotra1Minakshi Bhardwaj2Department of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaDepartment of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaDepartment of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaNeuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18contrast-enhanced computed tomographyhematuriaimmunohistochemistryneuroendocrine malignancyurinary bladder
spellingShingle Manjari Kishore
Purnima Malhotra
Minakshi Bhardwaj
Role of immunohistochemistry in diagnosis of a rare bladder tumor
Journal of Laboratory Physicians
contrast-enhanced computed tomography
hematuria
immunohistochemistry
neuroendocrine malignancy
urinary bladder
title Role of immunohistochemistry in diagnosis of a rare bladder tumor
title_full Role of immunohistochemistry in diagnosis of a rare bladder tumor
title_fullStr Role of immunohistochemistry in diagnosis of a rare bladder tumor
title_full_unstemmed Role of immunohistochemistry in diagnosis of a rare bladder tumor
title_short Role of immunohistochemistry in diagnosis of a rare bladder tumor
title_sort role of immunohistochemistry in diagnosis of a rare bladder tumor
topic contrast-enhanced computed tomography
hematuria
immunohistochemistry
neuroendocrine malignancy
urinary bladder
url http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18
work_keys_str_mv AT manjarikishore roleofimmunohistochemistryindiagnosisofararebladdertumor
AT purnimamalhotra roleofimmunohistochemistryindiagnosisofararebladdertumor
AT minakshibhardwaj roleofimmunohistochemistryindiagnosisofararebladdertumor