Role of immunohistochemistry in diagnosis of a rare bladder tumor
Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary ne...
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Format: | Article |
Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2019-01-01
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Series: | Journal of Laboratory Physicians |
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Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18 |
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author | Manjari Kishore Purnima Malhotra Minakshi Bhardwaj |
author_facet | Manjari Kishore Purnima Malhotra Minakshi Bhardwaj |
author_sort | Manjari Kishore |
collection | DOAJ |
description | Neuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics. |
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format | Article |
id | doaj.art-02640a23ac43442fb082f84038359e71 |
institution | Directory Open Access Journal |
issn | 0974-2727 0974-7826 |
language | English |
last_indexed | 2024-12-13T01:50:34Z |
publishDate | 2019-01-01 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | Article |
series | Journal of Laboratory Physicians |
spelling | doaj.art-02640a23ac43442fb082f84038359e712022-12-22T00:03:32ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262019-01-01110109109310.4103/JLP.JLP_119_18Role of immunohistochemistry in diagnosis of a rare bladder tumorManjari Kishore0Purnima Malhotra1Minakshi Bhardwaj2Department of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaDepartment of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaDepartment of Pathology, Postgraduate Institute of Medical Education and Research, Dr. Ram Manohar Lohia Hospital, New Delhi, IndiaNeuroendocrine tumors (NETs) are commonly located in the respiratory and gastrointestinal tract; however, these tumors can rarely be found in the urinary bladder. NETs comprise <1% of all bladder tumors; usually intermixed with urothelial carcinoma and its variants. We report a case of primary neuroendocrine carcinoma of urinary bladder in an adult female with a history of smoking and hematuria. The present case highlights the importance of immunohistochemistry in arriving at an accurate diagnosis and thereby differentiating this tumor from other clinical mimics.http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18contrast-enhanced computed tomographyhematuriaimmunohistochemistryneuroendocrine malignancyurinary bladder |
spellingShingle | Manjari Kishore Purnima Malhotra Minakshi Bhardwaj Role of immunohistochemistry in diagnosis of a rare bladder tumor Journal of Laboratory Physicians contrast-enhanced computed tomography hematuria immunohistochemistry neuroendocrine malignancy urinary bladder |
title | Role of immunohistochemistry in diagnosis of a rare bladder tumor |
title_full | Role of immunohistochemistry in diagnosis of a rare bladder tumor |
title_fullStr | Role of immunohistochemistry in diagnosis of a rare bladder tumor |
title_full_unstemmed | Role of immunohistochemistry in diagnosis of a rare bladder tumor |
title_short | Role of immunohistochemistry in diagnosis of a rare bladder tumor |
title_sort | role of immunohistochemistry in diagnosis of a rare bladder tumor |
topic | contrast-enhanced computed tomography hematuria immunohistochemistry neuroendocrine malignancy urinary bladder |
url | http://www.thieme-connect.de/DOI/DOI?10.4103/JLP.JLP_119_18 |
work_keys_str_mv | AT manjarikishore roleofimmunohistochemistryindiagnosisofararebladdertumor AT purnimamalhotra roleofimmunohistochemistryindiagnosisofararebladdertumor AT minakshibhardwaj roleofimmunohistochemistryindiagnosisofararebladdertumor |