A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections
Lesions commonly associated with HIV infection include oral candidiasis, herpes simplex infection, oral Kaposi’s sarcoma, hairy leukoplakia, periodontal diseases (linear gingival erythema and necrotizing ulcerative periodontitis), xerostomia, human papillomavirus-associated warts, aphthous ulcers, n...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/29/3/129 |
| _version_ | 1797446800435576832 |
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| author | Adriana Teodora Campeanu Elena Dumea Mihaela Rus Claudia Fodor Anita Cristina Ionescu Elena Mocanu Mihaela Botnarciuc Irina Magdalena Dumitru |
| author_facet | Adriana Teodora Campeanu Elena Dumea Mihaela Rus Claudia Fodor Anita Cristina Ionescu Elena Mocanu Mihaela Botnarciuc Irina Magdalena Dumitru |
| author_sort | Adriana Teodora Campeanu |
| collection | DOAJ |
| description | Lesions commonly associated with HIV infection include oral candidiasis, herpes simplex infection, oral Kaposi’s sarcoma, hairy leukoplakia, periodontal diseases (linear gingival erythema and necrotizing ulcerative periodontitis), xerostomia, human papillomavirus-associated warts, aphthous ulcers, non-Hodgkin’s lymphoma, histoplasmosis, carcinoma, exfoliative cheilitis, and HIV salivary gland disease. Non-Hodgkin’s lymphoma (NHL) is the most common cancer in people living with HIV (PLWH), and the incidence is increased for aggressive B-cell NHL. Plasmablastic lymphoma (PbL) is a rare and aggressive B-cell malignancy that is often unresponsive to chemotherapy and usually has a poor prognosis. We hereby present the case of a patient with a recent history of COVID-19 infection who was diagnosed with HIV and NHL, with manifestations in the oral cavity and a favorable evolution after the introduction of antiviral therapy, specific chemotherapy, and radiotherapy. Dental expertise is necessary for the appropriate management of oral manifestations of HIV infection or AIDS, and lymphoma should be included in the differential diagnosis of any oral lesions. |
| first_indexed | 2024-03-09T13:46:46Z |
| format | Article |
| id | doaj.art-0267758c2da640009b446b80a3438800 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T13:46:46Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-0267758c2da640009b446b80a34388002023-11-30T20:58:16ZengMDPI AGCurrent Oncology1198-00521718-77292022-03-012931537154310.3390/curroncol29030129A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 InfectionsAdriana Teodora Campeanu0Elena Dumea1Mihaela Rus2Claudia Fodor3Anita Cristina Ionescu4Elena Mocanu5Mihaela Botnarciuc6Irina Magdalena Dumitru7Doctoral School, “Ovidius” University of Constanta, 900470 Constanta, RomaniaFaculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaFaculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaClinical Infectious Diseases Hospital Constanta, 900709 Constanta, RomaniaDoctoral School, “Ovidius” University of Constanta, 900470 Constanta, RomaniaFaculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaFaculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaFaculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaLesions commonly associated with HIV infection include oral candidiasis, herpes simplex infection, oral Kaposi’s sarcoma, hairy leukoplakia, periodontal diseases (linear gingival erythema and necrotizing ulcerative periodontitis), xerostomia, human papillomavirus-associated warts, aphthous ulcers, non-Hodgkin’s lymphoma, histoplasmosis, carcinoma, exfoliative cheilitis, and HIV salivary gland disease. Non-Hodgkin’s lymphoma (NHL) is the most common cancer in people living with HIV (PLWH), and the incidence is increased for aggressive B-cell NHL. Plasmablastic lymphoma (PbL) is a rare and aggressive B-cell malignancy that is often unresponsive to chemotherapy and usually has a poor prognosis. We hereby present the case of a patient with a recent history of COVID-19 infection who was diagnosed with HIV and NHL, with manifestations in the oral cavity and a favorable evolution after the introduction of antiviral therapy, specific chemotherapy, and radiotherapy. Dental expertise is necessary for the appropriate management of oral manifestations of HIV infection or AIDS, and lymphoma should be included in the differential diagnosis of any oral lesions.https://www.mdpi.com/1718-7729/29/3/129HIVCOVID-19non-Hodgkin’s lymphomaEpstein–Barroral manifestation |
| spellingShingle | Adriana Teodora Campeanu Elena Dumea Mihaela Rus Claudia Fodor Anita Cristina Ionescu Elena Mocanu Mihaela Botnarciuc Irina Magdalena Dumitru A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections Current Oncology HIV COVID-19 non-Hodgkin’s lymphoma Epstein–Barr oral manifestation |
| title | A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections |
| title_full | A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections |
| title_fullStr | A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections |
| title_full_unstemmed | A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections |
| title_short | A Rare Case of Plasmablastic Lymphoma in a Patient with HIV and SARS-CoV-2 Infections |
| title_sort | rare case of plasmablastic lymphoma in a patient with hiv and sars cov 2 infections |
| topic | HIV COVID-19 non-Hodgkin’s lymphoma Epstein–Barr oral manifestation |
| url | https://www.mdpi.com/1718-7729/29/3/129 |
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