Paraoxonases at the Heart of Neurological Disorders

Paraoxonases at the Heart of Neurological Disorders

Paraoxonase enzymes serve as an important physiological redox system that participates in the protection against cellular injury caused by oxidative stress. The PON enzymes family consists of three members (PON-1, PON-2, and PON-3) that share a similar structure and location as a cluster on human ch...

Full description

Bibliographic Details
Main Authors:	Fatimah K. Khalaf, Jacob Connolly, Bella Khatib-Shahidi, Abdulsahib Albehadili, Iman Tassavvor, Meghana Ranabothu, Noha Eid, Prabhatchandra Dube, Samer J. Khouri, Deepak Malhotra, Steven T. Haller, David J. Kennedy
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	International Journal of Molecular Sciences
Subjects:	paraoxonases neurodegenerative diseases Parkinson’s disease Alzheimer’s disease
Online Access:	https://www.mdpi.com/1422-0067/24/8/6881

Similar Items

Paraoxonase-1 Regulation of Renal Inflammation and Fibrosis in Chronic Kidney Disease
by: Fatimah K. Khalaf, et al.
Published: (2022-04-01)

Cardioprotective Role for Paraoxonase-1 in Chronic Kidney Disease
by: Prabhatchandra Dube, et al.
Published: (2022-09-01)

A PON for All Seasons: Comparing Paraoxonase Enzyme Substrates, Activity and Action including the Role of PON3 in Health and Disease
by: Chrysan J. Mohammed, et al.
Published: (2022-03-01)

Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview
by: Débora Levy, et al.
Published: (2019-05-01)

Phytochemicals as Modulators of Paraoxonase-1 in Health and Diseases
by: Zahra Najafi Arab, et al.
Published: (2022-06-01)

Correlation of Paraoxonase-1 with the Severity of Crohn’s Disease
by: Katarzyna Szczeklik, et al.
Published: (2018-10-01)

The past and present of paraoxonase enzyme: Its role in the cardiovascular system and some diseases
by: Aydin Suleyman, et al.
Published: (2012-01-01)

Paraoxonase 1 and atherosclerosis
by: Paul N. Durrington, et al.
Published: (2023-02-01)

Modulation of paraoxonases during infectious diseases and its potential impact on atherosclerosis
by: Farid Ayman, et al.
Published: (2012-07-01)

The Effect of Rosmarinic Acid on Cell Viability, Steatosis, Paraoxonase-1, and Paraoxonase-3 Protein Levels in Palmitate-induced Non-alcoholic Fatty Liver Disease Model in HepG2 Cells
by: Esra YAKŞİ, et al.
Published: (2021-08-01)

Proteomic Exploration of Paraoxonase 1 Function in Health and Disease
by: Hieronim Jakubowski
Published: (2023-04-01)

Paraoxonase Role in Human Neurodegenerative Diseases
by: Cadiele Oliana Reichert, et al.
Published: (2020-12-01)

The Role of ‘Paraoxonase-1 Activity’ as an Antioxidant in Coronary Artery Diseases
by: Maharudra Shekhanawar, et al.
Published: (2013-07-01)

Investigation of Paraoxonase-1 Genotype and Enzyme-Kinetic Parameters in the Context of Cognitive Impairment in Parkinson’s Disease
by: Boštjan Petrič, et al.
Published: (2023-02-01)

Study of Paraoxonase 1 (PON1) Activity as an Independent Risk Factor in Coronary Artery Disease
by: Sangita M. Patil, et al.
Published: (2013-04-01)

Paraoxonase/Arylesterase Activity of Serum Paraoxonase-1 and Schizophrenia: A Systematic Review and Meta-Analysis
by: Angelo Zinellu, et al.
Published: (2023-07-01)

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients
by: Nurhan Sarioglu, et al.
Published: (2015-02-01)

Paraoxonase 1 gene (Gln192–Arg) polymorphism and the risk of coronary artery disease in type 2 diabetes mellitus
by: Mohamed Fahmy Elnoamany, et al.
Published: (2012-06-01)

Paraoxonase 1 Activity and Renal Replacement Therapy for Chronic Renal Failure: A Meta-Analysis
by: Jun Watanabe, et al.
Published: (2023-08-01)

Arylesterase Activity of Paraoxonase-1 in Serum and Cerebrospinal Fluid of Patients with Alzheimer’s Disease and Vascular Dementia
by: Arianna Romani, et al.
Published: (2020-05-01)

Dynamic changes of paraoxonase 1 activity towards paroxon and phenyl acetate during coronary artery surgery
by: Anna Wysocka, et al.
Published: (2017-04-01)

Arylesterase activity of paraoxonase 1 and intensity of oxidative processes in the blood of dialysis patients
by: L. Korol, et al.
Published: (2019-12-01)

Paraoxonase 1 Gene Polymorphisms as A Risk Factor of Coronary Artery Diseases
by: Ahmed El-Hassanin, et al.
Published: (2022-11-01)

Paraoxonase 1 and Chronic Kidney Disease: A Meta-Analysis
by: Jun Watanabe, et al.
Published: (2023-02-01)

Paraoxonase 1 and Chronic Obstructive Pulmonary Disease: A Meta-Analysis
by: Jun Watanabe, et al.
Published: (2021-11-01)

The correlation of paraoxonase (PON1) activity with lipid and lipoprotein levels differs with vascular disease status
by: Laura S. Rozek, et al.
Published: (2005-09-01)

Paraoxonase 1 Activity and Survival in Sepsis Patients
by: Volkan İnal, et al.
Published: (2015-06-01)

The Relevance of Noncoding DNA Variations of Paraoxonase Gene Cluster in Atherosclerosis-Related Diseases
by: Anna Wysocka, et al.
Published: (2021-02-01)

Association of Paraoxonase-1 and NT-proBNP with Clinical, Clinico-Pathologic and Echocardiographic Variables in Dogs with Mitral Valve Disease
by: Diana Rammal, et al.
Published: (2023-01-01)

Paraoxonase-1 and -3 Protein Expression in the Brain of the Tg2576 Mouse Model of Alzheimer’s Disease
by: Jose Gregorio Salazar, et al.
Published: (2021-02-01)

Evaluation of paraoxonase, malondialdehyde, and lipoprotein levels in patients with asymptomatic cholelithiasis
by: Aytac Atamer, et al.
Published: (2014-01-01)

Association between Paraoxonase/Arylesterase Activity of Serum PON-1 Enzyme and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
by: Gian Luca Erre, et al.
Published: (2022-11-01)

Caffeine Increases Apolipoprotein A-1 and Paraoxonase-1 but not Paraoxonase-3 Protein Levels in Human-Derived Liver (HepG2) Cells
by: Gülben Sayılan Özgün, et al.
Published: (2017-12-01)

Paraoxonase 1 as an important antiatherogenic agent
by: Ewa Lidia Krzewicka-Romaniuk, et al.
Published: (2019-01-01)

Paraoxonase enzyme activity and dyslipidemia in chronic kidney disease patients
by: Mehrdad Solati, et al.
Published: (2012-10-01)

Effect of Andrographolide on Paraoxonase 2 Expression in Male Wistar Rats
by: Reza Alipanah Moghadam, et al.
Published: (2018-05-01)

Modulação Dietética da Atividade da Paraoxonase: Revisão de Estudos em Humanos
by: Jaqueline Driemeyer Correia, et al.
Published: (2010-10-01)

Evaluation of paraoxonase, arylesterase, and homocysteine thiolactonase activities in patients with diabetes and incipient diabetes nephropathy
by: Ayan Durmu§, et al.
Published: (2019-01-01)

Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease
by: Cadiele Oliana Reichert, et al.
Published: (2019-07-01)

Oxidative Stress and Alterations of Paraoxonases in Atopic Dermatitis
by: Oriana Simonetti, et al.
Published: (2021-04-01)