Dietary supplementation of coenzyme Q10 plus multivitamins to hamper the ROS mediated cisplatin ototoxicity in humans: A pilot study

Dietary supplementation of coenzyme Q10 plus multivitamins to hamper the ROS mediated cisplatin ototoxicity in humans: A pilot study

Oxidative stress exerts major role in the pathogenesis of side effects of many antineoplastic drugs, including ototoxicity of cisplatin. In particular, increased levels of reactive oxygen species (ROS) represent one of the molecular mechanisms underlying the apoptosis of different types of hearing c...

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Bibliographic Details
Main Authors: Felice Scasso, Andrea Elio Sprio, Luciano Canobbio, Chiara Scanarotti, Giorgio Manini, Giovanni Nicolao Berta, Anna Maria Bassi
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Heliyon
Subjects:
Human toxicology
Food science
Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016321223

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