Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy

Introduction: Percutaneous transvenous mitral commissurotomy (PTMC) is one of the nonsurgical commissurotomy in patients with hemodynamically significant mitral stenosis. The aim of the present study is to assess the immediate, intermediate and long term outcomes of PTMC in relation to initial mitra...

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Main Authors: Satya Narayana Murthy Jayanthi Sriram, Balasubramaniyan Jayanthi Venkata, Thanikachalam Sadagopan, Muralidharan Thodi Ramamurthy
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:International Journal of Cardiology: Heart & Vasculature
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235290671500007X
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author Satya Narayana Murthy Jayanthi Sriram
Balasubramaniyan Jayanthi Venkata
Thanikachalam Sadagopan
Muralidharan Thodi Ramamurthy
author_facet Satya Narayana Murthy Jayanthi Sriram
Balasubramaniyan Jayanthi Venkata
Thanikachalam Sadagopan
Muralidharan Thodi Ramamurthy
author_sort Satya Narayana Murthy Jayanthi Sriram
collection DOAJ
description Introduction: Percutaneous transvenous mitral commissurotomy (PTMC) is one of the nonsurgical commissurotomy in patients with hemodynamically significant mitral stenosis. The aim of the present study is to assess the immediate, intermediate and long term outcomes of PTMC in relation to initial mitral valve score and to assess its impact on mitral valve area (MVA), clinical and hemodynamic parameters. Methods: It is a retrospective study on a total of 303 patients who underwent successful PTMC between 1994 and 2001, were called back and their preprocedural, immediate post and follow-up (4, 7 and 10 year.) data were analyzed. Echo was performed in patients before and after PTMC. The patients were divided into two groups, group-I with Wilkins score of ≤8 and group-II with Wilkins score between 8 and 12. Results: PTMC patients who have completed 4, 7 and 10 years of follow up revealed the mitral valve area, mean transmitral gradient and pulmonary artery pressures to be significantly different in both group-I and group-II. At all follow-up periods group-II showed higher restenosis than group-I, but its distribution between the groups was not statistically significant (χ2 = 0.029; p = 0.986). Furthermore, losses of the MVA during different periods of follow-up revealed a gradual increase in attrition. Conclusions: MV score, Mitral valve area, mitral gradient and pulmonary artery pressures appeared to influence the outcome of PTMC. A clear-cut prospective assessment of individual components of the mitral valve apparatus using 3-D echocardiographic images may provide a more precise prediction of the PTMC outcome based on its morphological abnormalities.
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spelling doaj.art-026cc6a73b1a4a2b9f30f6a183c55d552022-12-22T03:31:07ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672015-03-016C667010.1016/j.ijcha.2015.01.006Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomySatya Narayana Murthy Jayanthi SriramBalasubramaniyan Jayanthi VenkataThanikachalam SadagopanMuralidharan Thodi RamamurthyIntroduction: Percutaneous transvenous mitral commissurotomy (PTMC) is one of the nonsurgical commissurotomy in patients with hemodynamically significant mitral stenosis. The aim of the present study is to assess the immediate, intermediate and long term outcomes of PTMC in relation to initial mitral valve score and to assess its impact on mitral valve area (MVA), clinical and hemodynamic parameters. Methods: It is a retrospective study on a total of 303 patients who underwent successful PTMC between 1994 and 2001, were called back and their preprocedural, immediate post and follow-up (4, 7 and 10 year.) data were analyzed. Echo was performed in patients before and after PTMC. The patients were divided into two groups, group-I with Wilkins score of ≤8 and group-II with Wilkins score between 8 and 12. Results: PTMC patients who have completed 4, 7 and 10 years of follow up revealed the mitral valve area, mean transmitral gradient and pulmonary artery pressures to be significantly different in both group-I and group-II. At all follow-up periods group-II showed higher restenosis than group-I, but its distribution between the groups was not statistically significant (χ2 = 0.029; p = 0.986). Furthermore, losses of the MVA during different periods of follow-up revealed a gradual increase in attrition. Conclusions: MV score, Mitral valve area, mitral gradient and pulmonary artery pressures appeared to influence the outcome of PTMC. A clear-cut prospective assessment of individual components of the mitral valve apparatus using 3-D echocardiographic images may provide a more precise prediction of the PTMC outcome based on its morphological abnormalities.http://www.sciencedirect.com/science/article/pii/S235290671500007XRheumatic heartValve areaMitral stenosis
spellingShingle Satya Narayana Murthy Jayanthi Sriram
Balasubramaniyan Jayanthi Venkata
Thanikachalam Sadagopan
Muralidharan Thodi Ramamurthy
Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
International Journal of Cardiology: Heart & Vasculature
Rheumatic heart
Valve area
Mitral stenosis
title Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
title_full Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
title_fullStr Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
title_full_unstemmed Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
title_short Immediate, intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
title_sort immediate intermediate and long term clinical outcomes of percutaneous transvenous mitral commissurotomy
topic Rheumatic heart
Valve area
Mitral stenosis
url http://www.sciencedirect.com/science/article/pii/S235290671500007X
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