Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022
Abstract Background: Factors influencing excessive antimicrobial utilization in hospitalized patients remain poorly understood, particularly with the COVID-19 pandemic. Methods: In this retrospective cohort, we compared administrative data regarding antimicrobial prescriptions in hospitalized pa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2023-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X23004965/type/journal_article |
| _version_ | 1797394316244549632 |
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| author | Pamela Bailey Shujie Chen Majdi N. Al-Hasan Bankole Olatosi Xiaoming Li Jiajia Zhang |
| author_facet | Pamela Bailey Shujie Chen Majdi N. Al-Hasan Bankole Olatosi Xiaoming Li Jiajia Zhang |
| author_sort | Pamela Bailey |
| collection | DOAJ |
| description |
Abstract
Background:
Factors influencing excessive antimicrobial utilization in hospitalized patients remain poorly understood, particularly with the COVID-19 pandemic.
Methods:
In this retrospective cohort, we compared administrative data regarding antimicrobial prescriptions in hospitalized patients in South Carolina from March 2020 through September 2022. The study examined variables associated with antimicrobial use across demographics, COVID status, and length of stay, among other variables.
Results:
Significant relationships were seen with antimicrobial use in COVID-19 positive patients (OR 2.00, 95% Confidence Interval (CI): 1.9–2.1), young adults (OR 1.08, 95% CI: 0.99–1.12, COVID-19 positive Blacks and Hispanics (OR 1.06, 95% CI: 1.01–1.11, OR 1.05, 95% CI: 0.89–1.23), and COVID-19 positive patients with ≥2 comorbid conditions (OR 1.55, 95% CI: 1.43–1.68).
Discussion:
Further analysis in more than one healthcare system should explore these ecologic relationships further to understand if these are common trends to inform ongoing stewardship interventions.
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| first_indexed | 2024-03-09T00:17:54Z |
| format | Article |
| id | doaj.art-026cd7e6bece400e8e1af2d122e2ef92 |
| institution | Directory Open Access Journal |
| issn | 2732-494X |
| language | English |
| last_indexed | 2024-03-09T00:17:54Z |
| publishDate | 2023-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj.art-026cd7e6bece400e8e1af2d122e2ef922023-12-12T07:28:17ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2023-01-01310.1017/ash.2023.496Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022Pamela Bailey0https://orcid.org/0000-0002-6953-8955Shujie Chen1Majdi N. Al-Hasan2https://orcid.org/0000-0001-6501-492XBankole Olatosi3https://orcid.org/0000-0002-8295-8735Xiaoming Li4https://orcid.org/0000-0002-5555-9034Jiajia Zhang5Department of Internal Medicine, Division of Infectious Diseases, Prisma Health—Midlands, Columbia, SC, USA University of South Carolina School of Medicine, Columbia, SC, USADepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA Big Data Health Science Center, Arnold School of Public Health, University of South Carolina, Columbia, SC, USADepartment of Internal Medicine, Division of Infectious Diseases, Prisma Health—Midlands, Columbia, SC, USA University of South Carolina School of Medicine, Columbia, SC, USABig Data Health Science Center, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC, USABig Data Health Science Center, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina; Columbia, SC, USADepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA Big Data Health Science Center, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA Abstract Background: Factors influencing excessive antimicrobial utilization in hospitalized patients remain poorly understood, particularly with the COVID-19 pandemic. Methods: In this retrospective cohort, we compared administrative data regarding antimicrobial prescriptions in hospitalized patients in South Carolina from March 2020 through September 2022. The study examined variables associated with antimicrobial use across demographics, COVID status, and length of stay, among other variables. Results: Significant relationships were seen with antimicrobial use in COVID-19 positive patients (OR 2.00, 95% Confidence Interval (CI): 1.9–2.1), young adults (OR 1.08, 95% CI: 0.99–1.12, COVID-19 positive Blacks and Hispanics (OR 1.06, 95% CI: 1.01–1.11, OR 1.05, 95% CI: 0.89–1.23), and COVID-19 positive patients with ≥2 comorbid conditions (OR 1.55, 95% CI: 1.43–1.68). Discussion: Further analysis in more than one healthcare system should explore these ecologic relationships further to understand if these are common trends to inform ongoing stewardship interventions. https://www.cambridge.org/core/product/identifier/S2732494X23004965/type/journal_article |
| spellingShingle | Pamela Bailey Shujie Chen Majdi N. Al-Hasan Bankole Olatosi Xiaoming Li Jiajia Zhang Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 |
| title_full | Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 |
| title_fullStr | Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 |
| title_full_unstemmed | Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 |
| title_short | Ecologic analysis of antimicrobial use in South Carolina hospitals during 2020–2022 |
| title_sort | ecologic analysis of antimicrobial use in south carolina hospitals during 2020 2022 |
| url | https://www.cambridge.org/core/product/identifier/S2732494X23004965/type/journal_article |
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