Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion
This study presents a rare case of Rosai-Dorfman disease (RDD) with nasal and nasopharyngeal involvement, illustrating the complexities in diagnosing this enigmatic histiocytic disorder. RDD, characterized by massive, painless cervical lymphadenopathy, poses diagnostic challenges due to its diverse...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323008786 |
| _version_ | 1797357752484364288 |
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| author | Saubhagya Dhakal, MD Shailendra Katwal, MD Aastha Ghimire, MBBS Amrit Bhusal, MBBS Tek Nath Yogi, MBBS |
| author_facet | Saubhagya Dhakal, MD Shailendra Katwal, MD Aastha Ghimire, MBBS Amrit Bhusal, MBBS Tek Nath Yogi, MBBS |
| author_sort | Saubhagya Dhakal, MD |
| collection | DOAJ |
| description | This study presents a rare case of Rosai-Dorfman disease (RDD) with nasal and nasopharyngeal involvement, illustrating the complexities in diagnosing this enigmatic histiocytic disorder. RDD, characterized by massive, painless cervical lymphadenopathy, poses diagnostic challenges due to its diverse clinical presentations. In this case, a 38-year-old woman presented with a year-long history of neck swellings, nasal congestion, headaches, and sinusitis-like symptoms. Radiological imaging and histopathological examination revealed RDD involvement in the nasopharynx and paranasal sinuses. RDD diagnosis was confirmed through immunohistochemistry. The patient's unique symptoms emphasize the importance of considering RDD in the differential diagnosis of sinonasal masses with recurrent or unusual complaints. This case underscores the need for increased awareness, multidisciplinary management, and further research to enhance understanding and treatment of RDD, especially in extranodal presentations. |
| first_indexed | 2024-03-08T14:49:33Z |
| format | Article |
| id | doaj.art-0270965d40264aaab201dfe144282756 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-08T14:49:33Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-0270965d40264aaab201dfe1442827562024-01-11T04:30:56ZengElsevierRadiology Case Reports1930-04332024-03-01193956960Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussionSaubhagya Dhakal, MD0Shailendra Katwal, MD1Aastha Ghimire, MBBS2Amrit Bhusal, MBBS3Tek Nath Yogi, MBBS4Department of Radiology, National Academy of Medical Sciences, Kathmandu, NepalDepartment of Radiology, Dadeldhura Subregional Hospital, Dadeldhura, Nepal; Corresponding author.Department of Medicine, Patan Academy of Health Science, Kathmandu, NepalDepartment of Medicine, B.P Koirala Institute of Health Science, Sunsari, NepalDepartment of Medicine, B.P Koirala Institute of Health Science, Sunsari, NepalThis study presents a rare case of Rosai-Dorfman disease (RDD) with nasal and nasopharyngeal involvement, illustrating the complexities in diagnosing this enigmatic histiocytic disorder. RDD, characterized by massive, painless cervical lymphadenopathy, poses diagnostic challenges due to its diverse clinical presentations. In this case, a 38-year-old woman presented with a year-long history of neck swellings, nasal congestion, headaches, and sinusitis-like symptoms. Radiological imaging and histopathological examination revealed RDD involvement in the nasopharynx and paranasal sinuses. RDD diagnosis was confirmed through immunohistochemistry. The patient's unique symptoms emphasize the importance of considering RDD in the differential diagnosis of sinonasal masses with recurrent or unusual complaints. This case underscores the need for increased awareness, multidisciplinary management, and further research to enhance understanding and treatment of RDD, especially in extranodal presentations.http://www.sciencedirect.com/science/article/pii/S1930043323008786Rosai-Dorfman diseaseExtranodal presentationCase reportImmunohistochemistry |
| spellingShingle | Saubhagya Dhakal, MD Shailendra Katwal, MD Aastha Ghimire, MBBS Amrit Bhusal, MBBS Tek Nath Yogi, MBBS Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion Radiology Case Reports Rosai-Dorfman disease Extranodal presentation Case report Immunohistochemistry |
| title | Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion |
| title_full | Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion |
| title_fullStr | Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion |
| title_full_unstemmed | Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion |
| title_short | Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion |
| title_sort | uncommon presentation of rosai dorfman disease nasal and nasopharyngeal involvement a case report and discussion |
| topic | Rosai-Dorfman disease Extranodal presentation Case report Immunohistochemistry |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323008786 |
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