Supramolecular Enzymatic Labeling for Aptamer Switch-Based Electrochemical Biosensor

Supramolecular Enzymatic Labeling for Aptamer Switch-Based Electrochemical Biosensor

Here we report a novel labeling strategy for electrochemical aptasensors based on enzymatic marking via supramolecular host–guest interactions. This approach relies on the use of an adamantane-modified target-responsive hairpin DNA aptamer as an affinity bioreceptor, and a neoglycoconjugate of β-cyc...

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Bibliographic Details
Main Authors: Anabel Villalonga, Concepción Parrado, Raúl Díaz, Alfredo Sánchez, Beatriz Mayol, Paloma Martínez-Ruíz, Diana Vilela, Reynaldo Villalonga
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biosensors
Subjects:
aptamer
biosensor
carcinoembryonic antigen
cyclodextrin
gold nanostars
Online Access:https://www.mdpi.com/2079-6374/12/7/514

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