The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

Show other versions (1)

Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method. The thiosemicarbazone and semicarbazone derivatives of lapachol exhibited antim...

Full description

Bibliographic Details
Main Authors:	Marina Azevedo Souza, Susana Johann, Luciana Alves Rodrigues dos Santos Lima, Fernanda Fraga Campos, Isolda Castro Mendes, Heloisa Beraldo, Elaine Maria de Souza-Fagundes, Patricia Silva Cisalpino, Carlos Augusto Rosa, Tania Maria de Almeida Alves, Nivea Pereira de Sa, Carlos Leomar Zani
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2013-05-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	antimicrobial agents lapachol Paracoccidioides
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300342&lng=en&tlng=en

Similar Items

The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives
by: Marina Azevêdo Souza, et al.
Published: (2013-05-01)

Ciclização do lapachol induzida por sais de tálio III Cyclyzation of lapachol induced by thallium salts
by: Carlos Magno R. Ribeiro, et al.
Published: (2008-01-01)

New enamine derivatives of lapachol and biological activity
by: MAILCAR F. OLIVEIRA, et al.
Published: (2002-06-01)

Cytotoxic and DNA-topoisomerase effects of lapachol amine derivatives and interactions with DNA
by: A. Esteves-Souza, et al.
Published: (2007-10-01)

Embryo development alteration in rats treated with lapachol
by: Juliana Maganha, et al.
Published: (2006-11-01)

Atividade biológica do lapachol e de alguns derivados sobre o desenvolvimento fúngico e em germinação de sementes Biological activity of lapachol and some derivatives as antifungal and in seed germination
by: Marco Andre Alves de Souza, et al.
Published: (2008-01-01)

Synthesis of Lapachol and 4-Hydroxyquinazoline Derivatives as Candidates for Antimalarial Activity
by: Felipe Revoredo Benatti, et al.
Published: (2020-12-01)

INTERAÇÃO DO LAPACHOL COM NANOPLATAFORMAS MICELARES DRUG DELIVERY
by: Maycon Renan Santos Lima, et al.
Published: (2021-04-01)

Preclinical evaluation of L-fucoside from lapachol-loaded nanoemulsion as a strategy to breast cancer treatment
by: Sued Eustaquio Mendes Miranda, et al.
Published: (2024-01-01)

Antileishmanial activity of lapachol analogues
by: Nadja MF Lima, et al.
Published: (2004-11-01)

Aplicação termoanalítica no desenvolvimento e caracterização de micropartículas de PLGA contendo lapachol
by: J. A. SILVA, et al.
Published: (2009-05-01)

Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster
by: Wender Ferreira Costa, et al.
Published: (2010-01-01)

Preparação de derivados do lapachol em meio ácido e em meio básico: uma proposta de experimentos para a disciplina de Química Orgânica Experimental Preparation of lapachol derivatives in acid and base media: proposed experiments for Organic Chemistry laboratory classes
by: Ticiano Pereira Barbosa, et al.
Published: (2013-01-01)

Antimony(V) and Bismuth(V) Complexes of Lapachol: Synthesis, Crystal Structure and Cytotoxic Activity
by: Cynthia Demicheli, et al.
Published: (2011-12-01)

Preparação de derivados do lapachol em meio ácido e em meio básico: uma proposta de experimentos para a disciplina de Química Orgânica Experimental
by: Ticiano Pereira Barbosa, et al.
Published: (2013-01-01)

Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II
by: Huanli Xu, et al.
Published: (2016-11-01)

Density functional theory, molecular docking, In vitro and In vivo anti-inflammatory investigation of lapachol isolated from Fernandoa adenophylla
by: Abdur Rauf, et al.
Published: (2023-12-01)

Synthesis of novel naphthoquinone-spermidine conjugates and their effects on DNA-topoisomerases I and II-alpha
by: Cunha Andréa S., et al.
Published: (2006-01-01)

Synthesis of 2-hydroxy-3-(2-methyl-propenyl)-1,4-naphthoquinone and related oxime derivatives
by: Patricia S. Oliveira, et al.
Published: (2012-06-01)

Histopathological alterations induced by non-viable cells and biochemical fractions from Paracoccidioides brasiliensis in mice
by: J. S. Hamdan, et al.
Published: (1993-03-01)

A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells
by: Rone A. De Grandis, et al.
Published: (2021-06-01)

Paracoccidioides-host interaction: An overview on recent advances in the paracoccidioidomycosis
by: Haroldo Cesar de Oliveira, et al.
Published: (2015-11-01)

Associação entre paracoccidioidomicose e câncer Association between paracoccidioidomycosis and cancer
by: Gustavo da Silva Rodrigues, et al.
Published: (2010-06-01)

Blood shizonticidal activities of phenazines and naphthoquinoidal compounds against Plasmodium falciparum in vitro and in mice malaria studies
by: Nicolli Bellotti de Souza, et al.
Published: (2014-08-01)

Etymologia: Paracoccidioides
by: Lucas Nojosa Oliveira, et al.
Published: (2021-09-01)

PREPARATION AND CHARACTERIZATION OF NANOEMULSION CONTAINING A NATURAL NAPHTHOQUINONE
by: Fernando V. S. Rodrigues, et al.

Antifungal activity of extracts from Atacama Desert fungi againstParacoccidioides brasiliensis and identification ofAspergillus felis as a promising source of natural bioactive compounds
by: Graziele Mendes, et al.
Published: (2016-03-01)

Paracoccidioidomicose do sistema nervoso central: análise de 13 casos Central nervous system paracoccidioidomycosis: analysis os 13 cases
by: Walter J. Fagundes-Pereyra, et al.
Published: (2006-06-01)

In vitro antifungal activity of fatty acid methyl esters of the seeds of Annona cornifolia A.St.-Hil. (Annonaceae) against pathogenic fungus Paracoccidioides brasiliensis
by: Luciana Alves Rodrigues dos Santos Lima, et al.
Published: (2011-12-01)

Electrochemical and positron annihilation studies of semicarbazones and thiosemicarbazones derived from ferrocene
by: Graúdo José Eugênio J. C., et al.
Published: (2000-01-01)

Fast and cost-effective protocol to produce Paracoccidioides spp. antigens
by: Karolina Rosa Fernandes-Beraldo, et al.
Published: (2023-08-01)

2-Benzoylpyridine semicarbazone
by: Daniel F. de Lima, et al.
Published: (2008-01-01)

2-Hydroxy-5-nitrobenzaldehyde thiosemicarbazone
by: Alhadi, Abeer A., et al.
Published: (2008)

Synthesis and Pharmacological Activity of Diterpenylnaphthoquinone Derivatives
by: Guillermo Schmeda-Hirschmann, et al.
Published: (2011-10-01)

Paracoccidioides brasiliensis habitat: far beyond armadillo burrows?
by: Priscila Marques de Macedo, et al.
Published: (2020-07-01)

5-Bromo-1H-indole-3-carbaldehyde thiosemicarbazone
by: Rizal, Mohd Razali, et al.
Published: (2008)

Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro
by: Kaila P. Medina-Alarcón, et al.
Published: (2017-06-01)

Acometimento ósseo na paracoccidioidomicose crônica disseminada: relato dos primeiros casos no Rio Grande do Sul
by: Luiz Carlos Severo, et al.
Published: (1996-06-01)

Theoretical Insights into Different Complexation Modes of Dioxovanadium(V) Compounds with Pyridoxal Semicarbazone/Thiosemicarbazone/S-Methyl-iso-thiosemicarbazone Ligands
by: Odeh Abdullah Odeh Alshammari, et al.
Published: (2024-03-01)

Influence of the Paracoccidioides brasiliensis 14-3-3 and gp43 proteins on the induction of apoptosis in A549 epithelial cells
by: Julhiany de Fátima da Silva, et al.
Published: (2015-06-01)