The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

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Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method. The thiosemicarbazone and semicarbazone derivatives of lapachol exhibited antim...

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Bibliographic Details
Main Authors: Marina Azevedo Souza, Susana Johann, Luciana Alves Rodrigues dos Santos Lima, Fernanda Fraga Campos, Isolda Castro Mendes, Heloisa Beraldo, Elaine Maria de Souza-Fagundes, Patricia Silva Cisalpino, Carlos Augusto Rosa, Tania Maria de Almeida Alves, Nivea Pereira de Sa, Carlos Leomar Zani
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
antimicrobial agents
lapachol
Paracoccidioides
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300342&lng=en&tlng=en
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