The Mechanisms and Functions of GDF‐5 in Intervertebral Disc Degeneration

The Mechanisms and Functions of GDF‐5 in Intervertebral Disc Degeneration

Intervertebral disc degeneration (IDD) is widely recognized as the main cause of low back pain, which leads to disability in aging populations and induces great losses both socially and economically worldwide. Unfortunately, current treatments for IDD are aimed at relieving symptoms instead of prese...

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Bibliographic Details
Main Authors: Sheng Guo, Liqiang Cui, Changming Xiao, Chenglong Wang, Bin Zhu, Xueli Liu, Yujie Li, Xinyue Liu, Dingxuan Wang, Sen Li
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Orthopaedic Surgery
Subjects:
Biological therapy
Disc regeneration
Extracellular matrix metabolism
Growth and differentiation factor‐5
Intervertebral disc degeneration
Online Access:https://doi.org/10.1111/os.12942

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