Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia

Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia

The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910. The objective of the present study was to assess the presence of these two mutations in Brazili...

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Bibliographic Details
Main Authors:	A.C. Bulhões, H.A.S. Goldani, F.S. Oliveira, U.S. Matte, R.B. Mazzuca, T.R. Silveira
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2007-11-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Hydrogen breath test Lactase-phlorizin hydrolase Lactose intolerance Milk intolerance LCT polymorphism
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100004

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