Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients
Abstract Background Data regarding the long-term oncological outcomes of robotic gastrectomy (RG) are limited despite the increased commonality of this method as an alternative for gastric cancer treatment. Here, we conducted a meta-analysis to evaluate the long-term oncological outcomes of RG in co...
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | World Journal of Surgical Oncology |
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| Online Access: | http://link.springer.com/article/10.1186/s12957-019-1628-2 |
| _version_ | 1818300933249957888 |
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| author | Guixiang Liao Zhihong Zhao Muhammad Khan Yawei Yuan Xianming Li |
| author_facet | Guixiang Liao Zhihong Zhao Muhammad Khan Yawei Yuan Xianming Li |
| author_sort | Guixiang Liao |
| collection | DOAJ |
| description | Abstract Background Data regarding the long-term oncological outcomes of robotic gastrectomy (RG) are limited despite the increased commonality of this method as an alternative for gastric cancer treatment. Here, we conducted a meta-analysis to evaluate the long-term oncological outcomes of RG in comparison to that of laparoscopic gastrectomy (LG). Methods The PubMed, ISI Web of Science, EMBASE, and Cochrane Library databases were comprehensively searched for studies that compared RG and LG in terms of their long-term survival outcomes. The hazard ratios (HRs) of overall survival (OS), disease-free survival (DFS), and relapse-free survival (RFS) were obtained, while the odds ratio (OR) was recorded for the recurrence rate. A sensitivity analysis was performed. Egger’s test and Begg’s test were applied to evaluate publication bias. Results Eight studies were identified and involved 3410 gastric cancer patients (RG, 1009; LG, 2401). The two groups had no significant differences in OS (HR, 0.98; 95% CI, 0.80–1.20; P = 0.81), DFS (HR, 1.36; 95% CI, 0.33–5.59; P = 0.67), RFS (HR, 0.92; 95% CI, 0.72–1.19; P = 0.53), or recurrence rate (OR, 0.92; 95% CI, 0.71–1.19; P = 0.53). Moreover, the two techniques were comparable in length of hospital stay (LOS), postoperative complication rate, 30-day mortality rate, and rate of conversion to open surgery. Conclusions The long-term oncological outcomes, expressed as OS, DFS, RFS, and recurrence rate, were similar between RG and LG. However, more randomized controlled trials with rigorous study designs and patient cohorts are needed to evaluate the oncologic outcomes of RG in patients with gastric cancer. |
| first_indexed | 2024-12-13T05:14:59Z |
| format | Article |
| id | doaj.art-027bae4321b64923a104c348d7348846 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-13T05:14:59Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-027bae4321b64923a104c348d73488462022-12-21T23:58:27ZengBMCWorld Journal of Surgical Oncology1477-78192019-05-011711910.1186/s12957-019-1628-2Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patientsGuixiang Liao0Zhihong Zhao1Muhammad Khan2Yawei Yuan3Xianming Li4Department of Radiation Oncology, Shenzhen People’s Hospital, Second Clinical Medicine Centre, Jinan UniversityDepartment of Nephrology, Shenzhen People’s Hospital, Second Clinical Medicine Centre, Jinan UniversityDepartment of Oncology, First Affiliated Hospital of Anhui Medical UniversityDepartment of Radiation Oncology, Cancer Center of Guangzhou Medical UniversityDepartment of Radiation Oncology, Shenzhen People’s Hospital, Second Clinical Medicine Centre, Jinan UniversityAbstract Background Data regarding the long-term oncological outcomes of robotic gastrectomy (RG) are limited despite the increased commonality of this method as an alternative for gastric cancer treatment. Here, we conducted a meta-analysis to evaluate the long-term oncological outcomes of RG in comparison to that of laparoscopic gastrectomy (LG). Methods The PubMed, ISI Web of Science, EMBASE, and Cochrane Library databases were comprehensively searched for studies that compared RG and LG in terms of their long-term survival outcomes. The hazard ratios (HRs) of overall survival (OS), disease-free survival (DFS), and relapse-free survival (RFS) were obtained, while the odds ratio (OR) was recorded for the recurrence rate. A sensitivity analysis was performed. Egger’s test and Begg’s test were applied to evaluate publication bias. Results Eight studies were identified and involved 3410 gastric cancer patients (RG, 1009; LG, 2401). The two groups had no significant differences in OS (HR, 0.98; 95% CI, 0.80–1.20; P = 0.81), DFS (HR, 1.36; 95% CI, 0.33–5.59; P = 0.67), RFS (HR, 0.92; 95% CI, 0.72–1.19; P = 0.53), or recurrence rate (OR, 0.92; 95% CI, 0.71–1.19; P = 0.53). Moreover, the two techniques were comparable in length of hospital stay (LOS), postoperative complication rate, 30-day mortality rate, and rate of conversion to open surgery. Conclusions The long-term oncological outcomes, expressed as OS, DFS, RFS, and recurrence rate, were similar between RG and LG. However, more randomized controlled trials with rigorous study designs and patient cohorts are needed to evaluate the oncologic outcomes of RG in patients with gastric cancer.http://link.springer.com/article/10.1186/s12957-019-1628-2Robotic gastrectomyLaparoscopic surgeryGastric cancerOverall survival (OS)Prognosis |
| spellingShingle | Guixiang Liao Zhihong Zhao Muhammad Khan Yawei Yuan Xianming Li Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients World Journal of Surgical Oncology Robotic gastrectomy Laparoscopic surgery Gastric cancer Overall survival (OS) Prognosis |
| title | Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients |
| title_full | Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients |
| title_fullStr | Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients |
| title_full_unstemmed | Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients |
| title_short | Comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long-term oncological outcomes: a meta-analysis of 3410 gastric cancer patients |
| title_sort | comparative analysis of robotic gastrectomy and laparoscopic gastrectomy for gastric cancer in terms of their long term oncological outcomes a meta analysis of 3410 gastric cancer patients |
| topic | Robotic gastrectomy Laparoscopic surgery Gastric cancer Overall survival (OS) Prognosis |
| url | http://link.springer.com/article/10.1186/s12957-019-1628-2 |
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