Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions
Adjuvant endocrine therapy (AET) taken for a minimum of five years reduces the recurrence and mortality risks among women with hormone-sensitive breast cancer. However, adherence to AET is suboptimal. To guide the development of theory-based interventions to enhance AET adherence, we conducted a stu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | Pharmacy |
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| Online Access: | http://www.mdpi.com/2226-4787/6/2/53 |
| _version_ | 1798038286791344128 |
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| author | Brittany Humphries Stéphanie Collins Laurence Guillaumie Julie Lemieux Anne Dionne Louise Provencher Jocelyne Moisan Sophie Lauzier |
| author_facet | Brittany Humphries Stéphanie Collins Laurence Guillaumie Julie Lemieux Anne Dionne Louise Provencher Jocelyne Moisan Sophie Lauzier |
| author_sort | Brittany Humphries |
| collection | DOAJ |
| description | Adjuvant endocrine therapy (AET) taken for a minimum of five years reduces the recurrence and mortality risks among women with hormone-sensitive breast cancer. However, adherence to AET is suboptimal. To guide the development of theory-based interventions to enhance AET adherence, we conducted a study to explore beliefs regarding early adherence to AET. This qualitative study was guided by the Theory of Planned Behavior (TPB). We conducted focus groups and individual interviews among women prescribed AET in the last two years (n = 43). The topic guide explored attitudinal (perceived advantages and disadvantages), normative (perception of approval or disapproval), and control beliefs (barriers and facilitating factors) towards adhering to AET. Thematic analysis was conducted. Most women had a positive attitude towards AET regardless of their medication-taking behavior. The principal perceived advantage was protection against a recurrence while the principal inconvenience was side effects. Almost everyone approved of the woman taking her medication. The women mentioned facilitating factors to encourage medication-taking behaviors and cope with side effects. For adherent women, having trouble establishing a routine was their main barrier to taking medication. For non-adherent women, it was side effects affecting their quality of life. These findings could inform the development of community pharmacy-based adherence interventions. |
| first_indexed | 2024-04-11T21:38:08Z |
| format | Article |
| id | doaj.art-027d157dfb1945998ec2ee8727b2adf1 |
| institution | Directory Open Access Journal |
| issn | 2226-4787 |
| language | English |
| last_indexed | 2024-04-11T21:38:08Z |
| publishDate | 2018-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmacy |
| spelling | doaj.art-027d157dfb1945998ec2ee8727b2adf12022-12-22T04:01:41ZengMDPI AGPharmacy2226-47872018-06-01625310.3390/pharmacy6020053pharmacy6020053Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist InterventionsBrittany Humphries0Stéphanie Collins1Laurence Guillaumie2Julie Lemieux3Anne Dionne4Louise Provencher5Jocelyne Moisan6Sophie Lauzier7Population Health and Optimal Health Practices, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaPopulation Health and Optimal Health Practices, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaPopulation Health and Optimal Health Practices, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaOncology Research Unit, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaFaculty of Pharmacy, Université Laval, 1050 avenue de la Médecine, Quebec, QC G1V 0A6, CanadaOncology Research Unit, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaPopulation Health and Optimal Health Practices, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaPopulation Health and Optimal Health Practices, CHU de Quebec–Université Laval Research Centre, Hôpital du Saint-Sacrement, 1050 chemin Ste-Foy, Quebec, QC G1S 4L8, CanadaAdjuvant endocrine therapy (AET) taken for a minimum of five years reduces the recurrence and mortality risks among women with hormone-sensitive breast cancer. However, adherence to AET is suboptimal. To guide the development of theory-based interventions to enhance AET adherence, we conducted a study to explore beliefs regarding early adherence to AET. This qualitative study was guided by the Theory of Planned Behavior (TPB). We conducted focus groups and individual interviews among women prescribed AET in the last two years (n = 43). The topic guide explored attitudinal (perceived advantages and disadvantages), normative (perception of approval or disapproval), and control beliefs (barriers and facilitating factors) towards adhering to AET. Thematic analysis was conducted. Most women had a positive attitude towards AET regardless of their medication-taking behavior. The principal perceived advantage was protection against a recurrence while the principal inconvenience was side effects. Almost everyone approved of the woman taking her medication. The women mentioned facilitating factors to encourage medication-taking behaviors and cope with side effects. For adherent women, having trouble establishing a routine was their main barrier to taking medication. For non-adherent women, it was side effects affecting their quality of life. These findings could inform the development of community pharmacy-based adherence interventions.http://www.mdpi.com/2226-4787/6/2/53oncologybreast cancermedication adherencetamoxifenaromatase inhibitors qualitative research |
| spellingShingle | Brittany Humphries Stéphanie Collins Laurence Guillaumie Julie Lemieux Anne Dionne Louise Provencher Jocelyne Moisan Sophie Lauzier Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions Pharmacy oncology breast cancer medication adherence tamoxifen aromatase inhibitors qualitative research |
| title | Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions |
| title_full | Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions |
| title_fullStr | Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions |
| title_full_unstemmed | Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions |
| title_short | Women’s Beliefs on Early Adherence to Adjuvant Endocrine Therapy for Breast Cancer: A Theory-Based Qualitative Study to Guide the Development of Community Pharmacist Interventions |
| title_sort | women s beliefs on early adherence to adjuvant endocrine therapy for breast cancer a theory based qualitative study to guide the development of community pharmacist interventions |
| topic | oncology breast cancer medication adherence tamoxifen aromatase inhibitors qualitative research |
| url | http://www.mdpi.com/2226-4787/6/2/53 |
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