Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum
Purpose: To evaluate the risk factors of prolonged hospitalization in patients with hyperemesis gravidarum (HEG). Material and Methods: The medical records of 114 patients who were admitted to the Zekai Tahir Burak Womens Health Education and Research Hospital with a diagnosis of HEG in the period J...
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| Format: | Article |
| Language: | English |
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Cukurova University
2015-03-01
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| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
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| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=168724 |
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| author | Hasan Onur Topcu Can Tekin iskender Asli Oskovi Hakan Timur Korkut Daglar Nuri Danisman |
| author_facet | Hasan Onur Topcu Can Tekin iskender Asli Oskovi Hakan Timur Korkut Daglar Nuri Danisman |
| author_sort | Hasan Onur Topcu |
| collection | DOAJ |
| description | Purpose: To evaluate the risk factors of prolonged hospitalization in patients with hyperemesis gravidarum (HEG).
Material and Methods: The medical records of 114 patients who were admitted to the Zekai Tahir Burak Womens Health Education and Research Hospital with a diagnosis of HEG in the period January 2013 to June 2014 were analyzed retrospectively. Hospital stay of more than 4 days was considered as prolonged hospitalization. Ninety -three patients with HEG who needed hospitalization less than four days formed the control group and 21 patients with HEG who needed hospitalization equal to or longer than four days formed the study group. The variables regarding age, body mass index, week of pregnancy, number of parity, daily vomiting number, number of days in hospital, need of combined antiemetic use, complete blood count, biochemistry markers, hormone tests, urine analysis were evaluated to assess their relationship with the risk factors for prolonged hospitalization in patients with HEG.
Results: Twenty-one of 114 patients diagnosed with HEG had a prolonged hospital stay, with a mean stay of 5.1 days. Age, body mass index, week of pregnancy, need of using combined antiemetics, complete blood count parameters, liver and kidney function tests were not associated with the duration of hospitalization. Daily vomiting, maternal serum TSH levels and blood urea nitrogen levels were 2.4 +/- 1.3 vs 4.2 +/- 1.9; p= 0.01, 1.19 +/- 0.71 vs 0.82 +/- 0.67; p= 0.04, 21.2 +/- 6.4 vs 18.1 +/- 5.3; p= 0.03; respectively, and these differences were found to be statistically significant among groups. The serum maternal TSH < 0.1 and micro;IU/mL and vomiting and #8805; 5 per day were found to be significant indicators for longer hospitalization (OR = 4.05, 95%CI = 1.07-15.3; P <0.05, OR=9.55, 95%CI = 1.81-50.4 P <0.05; respectively).
Conclusion: Number of vomiting per day and maternal serum TSH levels could help physicians to estimate the risk of prolonged hospitalization; however further investigations are needed in large population studies. Identifying the high risk patients is important both for prevention of HEG and beginning appropriate antiemetic treatment to avoid complications to reduce the economic costs. [Cukurova Med J 2015; 40(1.000): 113-118] |
| first_indexed | 2024-04-10T10:37:17Z |
| format | Article |
| id | doaj.art-027e85ac34f14323810f862cd2aa7355 |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T10:37:17Z |
| publishDate | 2015-03-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-027e85ac34f14323810f862cd2aa73552023-02-15T16:20:47ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502015-03-01401113118168724Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis GravidarumHasan Onur Topcu0Can Tekin iskender1Asli Oskovi2Hakan Timur3Korkut Daglar4Nuri Danisman5Zekai Tahir Burak Women's Health Education and Research Hospital Zekai Tahir Burak Women's Health Education and Research Hospital Zekai Tahir Burak Women's Health Education and Research Hospital Zekai Tahir Burak Women's Health Education and Research Hospital Zekai Tahir Burak Women's Health Education and Research Hospital Zekai Tahir Burak Women's Health Education and Research HospitalPurpose: To evaluate the risk factors of prolonged hospitalization in patients with hyperemesis gravidarum (HEG). Material and Methods: The medical records of 114 patients who were admitted to the Zekai Tahir Burak Womens Health Education and Research Hospital with a diagnosis of HEG in the period January 2013 to June 2014 were analyzed retrospectively. Hospital stay of more than 4 days was considered as prolonged hospitalization. Ninety -three patients with HEG who needed hospitalization less than four days formed the control group and 21 patients with HEG who needed hospitalization equal to or longer than four days formed the study group. The variables regarding age, body mass index, week of pregnancy, number of parity, daily vomiting number, number of days in hospital, need of combined antiemetic use, complete blood count, biochemistry markers, hormone tests, urine analysis were evaluated to assess their relationship with the risk factors for prolonged hospitalization in patients with HEG. Results: Twenty-one of 114 patients diagnosed with HEG had a prolonged hospital stay, with a mean stay of 5.1 days. Age, body mass index, week of pregnancy, need of using combined antiemetics, complete blood count parameters, liver and kidney function tests were not associated with the duration of hospitalization. Daily vomiting, maternal serum TSH levels and blood urea nitrogen levels were 2.4 +/- 1.3 vs 4.2 +/- 1.9; p= 0.01, 1.19 +/- 0.71 vs 0.82 +/- 0.67; p= 0.04, 21.2 +/- 6.4 vs 18.1 +/- 5.3; p= 0.03; respectively, and these differences were found to be statistically significant among groups. The serum maternal TSH < 0.1 and micro;IU/mL and vomiting and #8805; 5 per day were found to be significant indicators for longer hospitalization (OR = 4.05, 95%CI = 1.07-15.3; P <0.05, OR=9.55, 95%CI = 1.81-50.4 P <0.05; respectively). Conclusion: Number of vomiting per day and maternal serum TSH levels could help physicians to estimate the risk of prolonged hospitalization; however further investigations are needed in large population studies. Identifying the high risk patients is important both for prevention of HEG and beginning appropriate antiemetic treatment to avoid complications to reduce the economic costs. [Cukurova Med J 2015; 40(1.000): 113-118]http://www.scopemed.org/fulltextpdf.php?mno=168724hyperemesis gravidarumrisk factorspregnancyhospitalization |
| spellingShingle | Hasan Onur Topcu Can Tekin iskender Asli Oskovi Hakan Timur Korkut Daglar Nuri Danisman Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum Çukurova Üniversitesi Tıp Fakültesi Dergisi hyperemesis gravidarum risk factors pregnancy hospitalization |
| title | Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum |
| title_full | Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum |
| title_fullStr | Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum |
| title_full_unstemmed | Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum |
| title_short | Risk Factors of Prolonged Hospitalization in Patients with Hyperemesis Gravidarum |
| title_sort | risk factors of prolonged hospitalization in patients with hyperemesis gravidarum |
| topic | hyperemesis gravidarum risk factors pregnancy hospitalization |
| url | http://www.scopemed.org/fulltextpdf.php?mno=168724 |
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