Development and characterization of two equine formulations towards SARS-CoV-2 proteins for the potential treatment of COVID-19
Abstract In the current global emergency due to SARS-CoV-2 outbreak, passive immunotherapy emerges as a promising treatment for COVID-19. Among animal-derived products, equine formulations are still the cornerstone therapy for treating envenomations due to animal bites and stings. Therefore, drawing...
Main Authors: | Guillermo León, María Herrera, Mariángela Vargas, Mauricio Arguedas, Andrés Sánchez, Álvaro Segura, Aarón Gómez, Gabriela Solano, Eugenia Corrales-Aguilar, Kenneth Risner, Aarthi Narayanan, Charles Bailey, Mauren Villalta, Andrés Hernández, Adriana Sánchez, Daniel Cordero, Daniela Solano, Gina Durán, Eduardo Segura, Maykel Cerdas, Deibid Umaña, Edwin Moscoso, Ricardo Estrada, Jairo Gutiérrez, Marcos Méndez, Ana Cecilia Castillo, Laura Sánchez, Ronald Sánchez, José María Gutiérrez, Cecilia Díaz, Alberto Alape |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-89242-z |
Similar Items
-
Comparison of adjuvant emulsions for their safety and ability to enhance the antibody response in horses immunized with African snake venoms
by: Mauricio Arguedas, et al.
Published: (2022-12-01) -
Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes
by: Rose Mary Huertas, et al.
Published: (2023-06-01) -
Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Bitis spp. and Echis spp. African snakes.
by: Aarón Gómez, et al.
Published: (2022-08-01) -
High Efficacy of Therapeutic Equine Hyperimmune Antibodies Against SARS-CoV-2 Variants of Concern
by: Andres Moreira-Soto, et al.
Published: (2021-09-01) -
In Vitro Tests for Assessing the Neutralizing Ability of Snake Antivenoms: Toward the 3Rs Principles
by: José María Gutiérrez, et al.
Published: (2021-01-01)