Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis
Background Pulmonary involvement is the main cause of mortality in cystic fibrosis (CF). Airway clearance techniques are non-pharmacological complement options for CF patients. The aim of this study was to evaluate the short-term outcome of airway cleaning treatment in patients with cystic fibrosis...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2019-01-01
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| Series: | International Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://ijp.mums.ac.ir/article_11399_2cbdb91f4dac441faa90a912aea06926.pdf |
| _version_ | 1798038483472744448 |
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| author | Masoumeh Ghasempour Nemat Bilan Mohammadamin Rezazadehsaatlou |
| author_facet | Masoumeh Ghasempour Nemat Bilan Mohammadamin Rezazadehsaatlou |
| author_sort | Masoumeh Ghasempour |
| collection | DOAJ |
| description | Background Pulmonary involvement is the main cause of mortality in cystic fibrosis (CF). Airway clearance techniques are non-pharmacological complement options for CF patients. The aim of this study was to evaluate the short-term outcome of airway cleaning treatment in patients with cystic fibrosis in a children's hospital. Materials and Methods This clinical trial study conducted on 40 CF patients referring to the specialized lung clinic of Tabriz Pediatric Center in Tabriz, Iran from April 2016 to April 2017. Patients were randomly divided into two equal case (PEP), and control (conventional) groups. The basic spirometry parameters were measured on the European Respiratory Society criteria. After therapeutic intervention, the patients were followed for the next six months and the number of hospital admissions were recorded. Results The mean of FEV1, FEV1/FVC and FEF25%-75% in the control group after treatment were 62.60±20.39, 86.70±19.39 and 55.20±32.78, respectively. Comparison of the control group means of FEV1, FEV1/FVC, and FEF25%-75% in the case group after intervention (57.52±14.62, 76.80±21.83 and 59.8±28.71, respectively) showed significant differences (p |
| first_indexed | 2024-04-11T21:40:50Z |
| format | Article |
| id | doaj.art-027fcc5706214bd6b64a3e6d67165f47 |
| institution | Directory Open Access Journal |
| issn | 2345-5047 2345-5055 |
| language | English |
| last_indexed | 2024-04-11T21:40:50Z |
| publishDate | 2019-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj.art-027fcc5706214bd6b64a3e6d67165f472022-12-22T04:01:35ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552019-01-01718881888810.22038/ijp.2018.34187.301911399Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic FibrosisMasoumeh Ghasempour0Nemat Bilan1Mohammadamin Rezazadehsaatlou2Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Tuberculosis and Lung Disease Research Center, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.Background Pulmonary involvement is the main cause of mortality in cystic fibrosis (CF). Airway clearance techniques are non-pharmacological complement options for CF patients. The aim of this study was to evaluate the short-term outcome of airway cleaning treatment in patients with cystic fibrosis in a children's hospital. Materials and Methods This clinical trial study conducted on 40 CF patients referring to the specialized lung clinic of Tabriz Pediatric Center in Tabriz, Iran from April 2016 to April 2017. Patients were randomly divided into two equal case (PEP), and control (conventional) groups. The basic spirometry parameters were measured on the European Respiratory Society criteria. After therapeutic intervention, the patients were followed for the next six months and the number of hospital admissions were recorded. Results The mean of FEV1, FEV1/FVC and FEF25%-75% in the control group after treatment were 62.60±20.39, 86.70±19.39 and 55.20±32.78, respectively. Comparison of the control group means of FEV1, FEV1/FVC, and FEF25%-75% in the case group after intervention (57.52±14.62, 76.80±21.83 and 59.8±28.71, respectively) showed significant differences (phttp://ijp.mums.ac.ir/article_11399_2cbdb91f4dac441faa90a912aea06926.pdfCystic fibrosisLung injuryPediatricsPositive expiratory pressure |
| spellingShingle | Masoumeh Ghasempour Nemat Bilan Mohammadamin Rezazadehsaatlou Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis International Journal of Pediatrics Cystic fibrosis Lung injury Pediatrics Positive expiratory pressure |
| title | Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis |
| title_full | Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis |
| title_fullStr | Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis |
| title_full_unstemmed | Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis |
| title_short | Positive Expiratory Pressure (PEP) versus Conventional Chest Physiotherapy in Pediatric Patients with Acute Exacerbation of Cystic Fibrosis |
| title_sort | positive expiratory pressure pep versus conventional chest physiotherapy in pediatric patients with acute exacerbation of cystic fibrosis |
| topic | Cystic fibrosis Lung injury Pediatrics Positive expiratory pressure |
| url | http://ijp.mums.ac.ir/article_11399_2cbdb91f4dac441faa90a912aea06926.pdf |
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