SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells

SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells

Cancer stem cells (CSCs) are responsible for the migration and recurrence of cancer progression. Small nucleolar RNAs (snoRNAs) play important roles in tumor development. However, how snoRNAs contribute to the regulation of the stemness of ovarian CSCs (OCSCs) remains unclear. In the present study,...

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Bibliographic Details
Main Authors: Liwen Zhang, Rong Ma, Mengcong Gao, Yanyun Zhao, Xuemei Lv, Wenjing Zhu, Li Han, Panpan Su, Yue Fan, Yuanyuan Yan, Lin Zhao, Heyao Ma, Minjie Wei, Miao He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SNORA72
ovarian cancer stem cells (OCSCs)
Notch1
c-Myc
stemness
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.583087/full

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