Single-Cell Transcriptome Profiling Signatures and Alterations of Microglia Associated With Glioblastoma Associate Microglia Contribution to Tumor Formation

Single-Cell Transcriptome Profiling Signatures and Alterations of Microglia Associated With Glioblastoma Associate Microglia Contribution to Tumor Formation

Glioblastoma (GBM), which occasionally occurs in pediatric patients, is the most common tumor of the central nervous system in adults. Clinically, GBM is classified as low-grade to high-grade (from 1 to 4) and is characterized by late discovery, limited effective treatment methods, and poor efficacy...

Full description

Bibliographic Details
Main Authors: Hailong Xia, Lei Deng, Shu Meng, Xipeng Liu, Chao Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Pathology and Oncology Research
Subjects:
GBM
single-sell RNA-seq
microglia
tumor immune microenvironment
aged microglia
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610067/full

Similar Items

Similar Items