Metabolic effects of prolactin and the role of dopamine agonists: A review
Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin le...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1002320/full |
| _version_ | 1797997668902895616 |
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| author | Polly Kirsch Jessica Kunadia Shruti Shah Nidhi Agrawal |
| author_facet | Polly Kirsch Jessica Kunadia Shruti Shah Nidhi Agrawal |
| author_sort | Polly Kirsch |
| collection | DOAJ |
| description | Prolactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin levels could also be metabolically unfavorable. This review discusses the pathophysiology of prolactin related metabolic changes, and the less commonly recognized effects of prolactin on adipose tissue, pancreas, liver, and small bowel. Furthermore, the effect of dopamine agonists on the metabolic profiles of patients with hyperprolactinemia are discussed as well. |
| first_indexed | 2024-04-11T10:36:23Z |
| format | Article |
| id | doaj.art-028a803bdff74de580b168c380095724 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-11T10:36:23Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-028a803bdff74de580b168c3800957242022-12-22T04:29:17ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-09-011310.3389/fendo.2022.10023201002320Metabolic effects of prolactin and the role of dopamine agonists: A reviewPolly Kirsch0Jessica Kunadia1Shruti Shah2Nidhi Agrawal3New York University (NYU) Grossman School of Medicine, NYU Langone Health, New York, NY, United StatesDepartment of Medicine, NYU Langone Health, New York, NY, United StatesNew York University (NYU) Grossman School of Medicine, NYU Langone Health, New York, NY, United StatesDepartment of Medicine, NYU Langone Health, New York, NY, United StatesProlactin is a polypeptide hormone that is well known for its role in reproductive physiology. Recent studies highlight its role in neurohormonal appetite regulation and metabolism. Elevated prolactin levels are widely associated with worsening metabolic disease, but it appears that low prolactin levels could also be metabolically unfavorable. This review discusses the pathophysiology of prolactin related metabolic changes, and the less commonly recognized effects of prolactin on adipose tissue, pancreas, liver, and small bowel. Furthermore, the effect of dopamine agonists on the metabolic profiles of patients with hyperprolactinemia are discussed as well.https://www.frontiersin.org/articles/10.3389/fendo.2022.1002320/fullprolactinhyperprolactinemiaprolactinomametabolic syndromepituitarymetabolic dysfunction |
| spellingShingle | Polly Kirsch Jessica Kunadia Shruti Shah Nidhi Agrawal Metabolic effects of prolactin and the role of dopamine agonists: A review Frontiers in Endocrinology prolactin hyperprolactinemia prolactinoma metabolic syndrome pituitary metabolic dysfunction |
| title | Metabolic effects of prolactin and the role of dopamine agonists: A review |
| title_full | Metabolic effects of prolactin and the role of dopamine agonists: A review |
| title_fullStr | Metabolic effects of prolactin and the role of dopamine agonists: A review |
| title_full_unstemmed | Metabolic effects of prolactin and the role of dopamine agonists: A review |
| title_short | Metabolic effects of prolactin and the role of dopamine agonists: A review |
| title_sort | metabolic effects of prolactin and the role of dopamine agonists a review |
| topic | prolactin hyperprolactinemia prolactinoma metabolic syndrome pituitary metabolic dysfunction |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1002320/full |
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