Vaccination with Deglycosylated Modified Hemagglutinin Broadly Protects against Influenza Virus Infection in Mice and Ferrets

Recent efforts have been directed toward the development of universal influenza vaccines inducing broadly neutralizing antibodies to conserved antigenic supersites of Hemagglutinin (HA). Although several studies raise the importance of glycosylation in HA antigen design, whether this theory can be w...

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Bibliographic Details
Main Authors: Limin Zhang, Junyu Chen, Chenguang Shen, Guosong Wang, Zhen Lu, Dian Zeng, Ying Gao, Huiqing Chen, Ningshao Xia, Yixin Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/8/1304