Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

Type of RNA Packed in VLPs Impacts IgG Class Switching—Implications for an Influenza Vaccine Design

Nucleic acid packed within virus-like particles (VLPs) is shown to shape the immune response and to induce stronger B cell responses in different immunisation models. Here, using a VLP displaying the highly conserved extracellular domain of the M2 protein (M2e) from the influenza viruses as an antig...

Full description

Bibliographic Details
Main Authors: Ariane C. Gomes, E. S. Roesti, Aadil El-Turabi, Martin F. Bachmann
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Vaccines
Subjects:
VLPs
RNA
TLR7
IgG
Online Access:https://www.mdpi.com/2076-393X/7/2/47

Similar Items

Similar Items