Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury
<p>Abstract</p> <p>Background</p> <p>Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in very preterm infants who were mechanically ventilated for respiratory...
Main Authors: | Boersma Hester, Laghmani El Houari, Walther Frans J, de Visser Yvonne P, van der Laarse Arnoud, Wagenaar Gerry TM |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-04-01
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Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/10/1/30 |
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