17β-Estradiol Modulates SIRT1 and Halts Oxidative Stress-Mediated Cognitive Impairment in a Male Aging Mouse Model

17β-Estradiol Modulates SIRT1 and Halts Oxidative Stress-Mediated Cognitive Impairment in a Male Aging Mouse Model

Oxidative stress has been considered the main mediator in neurodegenerative disease and in normal aging processes. Several studies have reported that the accumulation of reactive oxygen species (ROS), elevated oxidative stress, and neuroinflammation result in cellular malfunction. These conditions l...

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Bibliographic Details
Main Authors:	Mehtab Khan, Rahat Ullah, Shafiq Ur Rehman, Shahid Ali Shah, Kamran Saeed, Tahir Muhammad, Hyun Young Park, Myeung Hoon Jo, Kyonghwan Choe, Bart P.F. Rutten, Myeong Ok Kim
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Cells
Subjects:	<span style="font-variant: small-caps">d</span>-galactose 17β-Estradiol SIRT1 ROS neuroinflammation neurodegeneration
Online Access:	https://www.mdpi.com/2073-4409/8/8/928

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