Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
Obstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck ca...
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Format: | Article |
Language: | English |
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MDPI AG
2021-10-01
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Series: | Medicina |
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Online Access: | https://www.mdpi.com/1648-9144/57/11/1174 |
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author | Christopher Seifen Tilman Huppertz Christoph Matthias Haralampos Gouveris |
author_facet | Christopher Seifen Tilman Huppertz Christoph Matthias Haralampos Gouveris |
author_sort | Christopher Seifen |
collection | DOAJ |
description | Obstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck cancer, a condition that ranks among the top ten most common types of cancer worldwide. Routinely, patients with head and neck cancer are treated with surgery, radiation therapy, chemotherapy, immunotherapy or a combination of these, all possibly interfering with the anatomy of the oral cavity, pharynx or larynx. Thus, cancer treatment might worsen already existing obstructive sleep apnea or trigger its occurrence. Hypoxia, the hallmark feature of obstructive sleep apnea, has an impact on cancer biology and its cure. Early diagnosis and sufficient treatment of coexisting obstructive sleep apnea in patients with head and neck cancer may improve quality of life and could also potentially improve oncological outcomes. |
first_indexed | 2024-03-10T05:17:22Z |
format | Article |
id | doaj.art-029c6b91519f4b2a97b150f63a339e26 |
institution | Directory Open Access Journal |
issn | 1010-660X 1648-9144 |
language | English |
last_indexed | 2024-03-10T05:17:22Z |
publishDate | 2021-10-01 |
publisher | MDPI AG |
record_format | Article |
series | Medicina |
spelling | doaj.art-029c6b91519f4b2a97b150f63a339e262023-11-23T00:16:48ZengMDPI AGMedicina1010-660X1648-91442021-10-015711117410.3390/medicina57111174Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?Christopher Seifen0Tilman Huppertz1Christoph Matthias2Haralampos Gouveris3Hals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyObstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck cancer, a condition that ranks among the top ten most common types of cancer worldwide. Routinely, patients with head and neck cancer are treated with surgery, radiation therapy, chemotherapy, immunotherapy or a combination of these, all possibly interfering with the anatomy of the oral cavity, pharynx or larynx. Thus, cancer treatment might worsen already existing obstructive sleep apnea or trigger its occurrence. Hypoxia, the hallmark feature of obstructive sleep apnea, has an impact on cancer biology and its cure. Early diagnosis and sufficient treatment of coexisting obstructive sleep apnea in patients with head and neck cancer may improve quality of life and could also potentially improve oncological outcomes.https://www.mdpi.com/1648-9144/57/11/1174obstructive sleep apneahead and neck cancercomorbidityoutcomereview |
spellingShingle | Christopher Seifen Tilman Huppertz Christoph Matthias Haralampos Gouveris Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? Medicina obstructive sleep apnea head and neck cancer comorbidity outcome review |
title | Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? |
title_full | Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? |
title_fullStr | Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? |
title_full_unstemmed | Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? |
title_short | Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity? |
title_sort | obstructive sleep apnea in patients with head and neck cancer more than just a comorbidity |
topic | obstructive sleep apnea head and neck cancer comorbidity outcome review |
url | https://www.mdpi.com/1648-9144/57/11/1174 |
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