Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?

Obstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck ca...

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Main Authors: Christopher Seifen, Tilman Huppertz, Christoph Matthias, Haralampos Gouveris
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/57/11/1174
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author Christopher Seifen
Tilman Huppertz
Christoph Matthias
Haralampos Gouveris
author_facet Christopher Seifen
Tilman Huppertz
Christoph Matthias
Haralampos Gouveris
author_sort Christopher Seifen
collection DOAJ
description Obstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck cancer, a condition that ranks among the top ten most common types of cancer worldwide. Routinely, patients with head and neck cancer are treated with surgery, radiation therapy, chemotherapy, immunotherapy or a combination of these, all possibly interfering with the anatomy of the oral cavity, pharynx or larynx. Thus, cancer treatment might worsen already existing obstructive sleep apnea or trigger its occurrence. Hypoxia, the hallmark feature of obstructive sleep apnea, has an impact on cancer biology and its cure. Early diagnosis and sufficient treatment of coexisting obstructive sleep apnea in patients with head and neck cancer may improve quality of life and could also potentially improve oncological outcomes.
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spelling doaj.art-029c6b91519f4b2a97b150f63a339e262023-11-23T00:16:48ZengMDPI AGMedicina1010-660X1648-91442021-10-015711117410.3390/medicina57111174Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?Christopher Seifen0Tilman Huppertz1Christoph Matthias2Haralampos Gouveris3Hals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyHals-, Nasen-, Ohrenklinik und Poliklinik, Universitätsmedizin der Johann Gutenberg—Universität Mainz, 55131 Mainz, GermanyObstructive sleep apnea is the most common type of sleep-disordered breathing with growing prevalence. Its presence has been associated with poor quality of life and serious comorbidities. There is increasing evidence for coexisting obstructive sleep apnea in patients suffering from head and neck cancer, a condition that ranks among the top ten most common types of cancer worldwide. Routinely, patients with head and neck cancer are treated with surgery, radiation therapy, chemotherapy, immunotherapy or a combination of these, all possibly interfering with the anatomy of the oral cavity, pharynx or larynx. Thus, cancer treatment might worsen already existing obstructive sleep apnea or trigger its occurrence. Hypoxia, the hallmark feature of obstructive sleep apnea, has an impact on cancer biology and its cure. Early diagnosis and sufficient treatment of coexisting obstructive sleep apnea in patients with head and neck cancer may improve quality of life and could also potentially improve oncological outcomes.https://www.mdpi.com/1648-9144/57/11/1174obstructive sleep apneahead and neck cancercomorbidityoutcomereview
spellingShingle Christopher Seifen
Tilman Huppertz
Christoph Matthias
Haralampos Gouveris
Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
Medicina
obstructive sleep apnea
head and neck cancer
comorbidity
outcome
review
title Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
title_full Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
title_fullStr Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
title_full_unstemmed Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
title_short Obstructive Sleep Apnea in Patients with Head and Neck Cancer—More than Just a Comorbidity?
title_sort obstructive sleep apnea in patients with head and neck cancer more than just a comorbidity
topic obstructive sleep apnea
head and neck cancer
comorbidity
outcome
review
url https://www.mdpi.com/1648-9144/57/11/1174
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