Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism

Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism

Abstract Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the effect of ISL in protecting against the inj...

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Detalhes bibliográficos
Principais autores: Xiaozhong Huang, Yujuan Shi, Hongjin Chen, Rongrong Le, Xiaohua Gong, Ke Xu, Qihan Zhu, Feixia Shen, Zimiao Chen, Xuemei Gu, Xiaojun Chen, Xiong Chen
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2020-12-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-020-03260-9

Internet

https://doi.org/10.1038/s41419-020-03260-9

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