Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor
Supramolecular recognition of dopamine by two quinoxaline cavitands was studied in solution by fluorescence titrations, ESI-MS and ROESY measurements. In addition, the tetraquinoxaline cavitand was dropped onto a siloxane-based polymeric solid support, obtaining a sensor able to detect dopamine in a...
| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
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MDPI AG
2022-11-01
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| Serie: | Molecules |
| Ämnen: | |
| Länkar: | https://www.mdpi.com/1420-3049/27/21/7503 |
| _version_ | 1827645899350736896 |
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| author | Rossella Santonocito Nunzio Tuccitto Andrea Pappalardo Giuseppe Trusso Sfrazzetto |
| author_facet | Rossella Santonocito Nunzio Tuccitto Andrea Pappalardo Giuseppe Trusso Sfrazzetto |
| author_sort | Rossella Santonocito |
| collection | DOAJ |
| description | Supramolecular recognition of dopamine by two quinoxaline cavitands was studied in solution by fluorescence titrations, ESI-MS and ROESY measurements. In addition, the tetraquinoxaline cavitand was dropped onto a siloxane-based polymeric solid support, obtaining a sensor able to detect dopamine in a linear range of concentrations 10 Mm–100 pM, with a detection limit of 1 pM, much lower than the normal concentration values in the common human fluids (plasma, urine and saliva), by using a simple smartphone as detector. This sensor shows also good selectivity for dopamine respect to the other common analytes contained in a saliva sample and can be reused after acid–base cycles, paving the way for the realization of real practical sensor for human dopamine detection. |
| first_indexed | 2024-03-09T18:47:34Z |
| format | Article |
| id | doaj.art-029cc2208a294bf194e7e4730b3f9372 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T18:47:34Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-029cc2208a294bf194e7e4730b3f93722023-11-24T06:05:19ZengMDPI AGMolecules1420-30492022-11-012721750310.3390/molecules27217503Smartphone-Based Dopamine Detection by Fluorescent Supramolecular SensorRossella Santonocito0Nunzio Tuccitto1Andrea Pappalardo2Giuseppe Trusso Sfrazzetto3Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, ItalyDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, ItalyDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, ItalyDepartment of Chemical Sciences, University of Catania, Viale A. Doria 6, 95100 Catania, ItalySupramolecular recognition of dopamine by two quinoxaline cavitands was studied in solution by fluorescence titrations, ESI-MS and ROESY measurements. In addition, the tetraquinoxaline cavitand was dropped onto a siloxane-based polymeric solid support, obtaining a sensor able to detect dopamine in a linear range of concentrations 10 Mm–100 pM, with a detection limit of 1 pM, much lower than the normal concentration values in the common human fluids (plasma, urine and saliva), by using a simple smartphone as detector. This sensor shows also good selectivity for dopamine respect to the other common analytes contained in a saliva sample and can be reused after acid–base cycles, paving the way for the realization of real practical sensor for human dopamine detection.https://www.mdpi.com/1420-3049/27/21/7503cavitanddopaminesupramolecularsmartphonesaliva |
| spellingShingle | Rossella Santonocito Nunzio Tuccitto Andrea Pappalardo Giuseppe Trusso Sfrazzetto Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor Molecules cavitand dopamine supramolecular smartphone saliva |
| title | Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor |
| title_full | Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor |
| title_fullStr | Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor |
| title_full_unstemmed | Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor |
| title_short | Smartphone-Based Dopamine Detection by Fluorescent Supramolecular Sensor |
| title_sort | smartphone based dopamine detection by fluorescent supramolecular sensor |
| topic | cavitand dopamine supramolecular smartphone saliva |
| url | https://www.mdpi.com/1420-3049/27/21/7503 |
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