Campylobacter jejuni extracellular vesicles harboring cytolethal distending toxin bind host cell glycans and induce cell cycle arrest in host cells

Campylobacter jejuni extracellular vesicles harboring cytolethal distending toxin bind host cell glycans and induce cell cycle arrest in host cells

ABSTRACTCytolethal distending toxins (CDTs) are released by Gram-negative pathogens into the extracellular medium as free toxin or associated with extracellular vesicles (EVs), commonly known as outer membrane vesicles (OMVs). CDT production by the gastrointestinal pathogen Campylobacter jejuni has...

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Bibliographic Details
Main Authors: Lena Hoang My Le, Bassam Elgamoudi, Nina Colon, Angus Cramond, Frederic Poly, Le Ying, Victoria Korolik, Richard L. Ferrero
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:Microbiology Spectrum
Subjects:
outer membrane vesicles
OMVs
Campylobacter jejuni
campylobacter
toxins
cytolethal distending toxin
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03232-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03232-23

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