The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors
Abstract Background This retrospective study aimed to evaluate the factors influencing the accuracy of Endoscopic Ultrasonography (EUS) as a preoperative assessment for gastrointestinal tumors. Methods A total of 261 patients with 264 gastrointestinal tumors were enrolled in the study. The parameter...
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Wiley
2023-02-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.5305 |
| _version_ | 1797893195492753408 |
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| author | Yan Zhao Mudan Ren Ai Jia Juan Zhang Shuying Wang Qian Zhao Guohong Cai Shuixiang He |
| author_facet | Yan Zhao Mudan Ren Ai Jia Juan Zhang Shuying Wang Qian Zhao Guohong Cai Shuixiang He |
| author_sort | Yan Zhao |
| collection | DOAJ |
| description | Abstract Background This retrospective study aimed to evaluate the factors influencing the accuracy of Endoscopic Ultrasonography (EUS) as a preoperative assessment for gastrointestinal tumors. Methods A total of 261 patients with 264 gastrointestinal tumors were enrolled in the study. The parameters of the gastrointestinal lesions examined under EUS and their pathology were recorded and analyzed. Results The accuracy of EUS for detecting intramucosal lesions and subepithelial lesions (SELs) were 83.6% and 91.4%, respectively. One hundred and ninety‐four (73.5%) lesions originated from the mucous layer, as determined by pre‐operation EUS examinations. The accuracy of EUS in predicting the correct T stage for intramucosal lesions in the gastric region, esophagus, and colorectum was 77%, 71.8%, and 84.6%, respectively. According to the Paris endoscopic classification, the distribution of macroscopic patterns was different between the EUS‐pathology conformity and nonconformity groups (p = 0.018). In the nonconformity group, 48.6% of erosive lesions were classified as 0‐IIc, 0‐IIa + IIc, 0‐IIc + IIa or 0‐III macroscopic patterns compared with 26% patients in the conformity group (p = 0.025). Univariate analyses demonstrated that ulcerative lesions (OR = 7.516, 95% Confidence Interval [CI] 2.574–21.952, p < 0.001), location at the cardia of the stomach (OR = 3.619, 95%CI 1.076–12.168, p = 0.038), malignant tumor (OR = 2.920, 95%CI 1.339–6.368, p = 0.007) were significantly associated with EUS inaccuracy. Multivariate logistic regression analyses showed that ulcer was an independent risk factor associated with EUS inaccuracy, with odds ratios of 5.094 (95% CI: 1.641–15.807, p = 0.005). Conclusions Our findings suggested that EUS is a reliable and easy‐to‐use diagnostic tool in decision‐making regarding appropriate endoscopic treatment for gastrointestinal tumors. However, the diagnostic accuracy of EUS appeared questionable in the presence of ulceration. |
| first_indexed | 2024-04-10T06:49:02Z |
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| id | doaj.art-02a358cf7204479b964e083fec9f242f |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-10T06:49:02Z |
| publishDate | 2023-02-01 |
| publisher | Wiley |
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| series | Cancer Medicine |
| spelling | doaj.art-02a358cf7204479b964e083fec9f242f2023-02-28T08:51:57ZengWileyCancer Medicine2045-76342023-02-011244321433110.1002/cam4.5305The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumorsYan Zhao0Mudan Ren1Ai Jia2Juan Zhang3Shuying Wang4Qian Zhao5Guohong Cai6Shuixiang He7Department of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaDepartment of Nuclear Medicine Xijing Hospital, Fourth Military Medical University Xi'an ChinaDepartment of Gastroenterology First Affiliated Hospital of Xi'an Jiaotong University Xi'an ChinaAbstract Background This retrospective study aimed to evaluate the factors influencing the accuracy of Endoscopic Ultrasonography (EUS) as a preoperative assessment for gastrointestinal tumors. Methods A total of 261 patients with 264 gastrointestinal tumors were enrolled in the study. The parameters of the gastrointestinal lesions examined under EUS and their pathology were recorded and analyzed. Results The accuracy of EUS for detecting intramucosal lesions and subepithelial lesions (SELs) were 83.6% and 91.4%, respectively. One hundred and ninety‐four (73.5%) lesions originated from the mucous layer, as determined by pre‐operation EUS examinations. The accuracy of EUS in predicting the correct T stage for intramucosal lesions in the gastric region, esophagus, and colorectum was 77%, 71.8%, and 84.6%, respectively. According to the Paris endoscopic classification, the distribution of macroscopic patterns was different between the EUS‐pathology conformity and nonconformity groups (p = 0.018). In the nonconformity group, 48.6% of erosive lesions were classified as 0‐IIc, 0‐IIa + IIc, 0‐IIc + IIa or 0‐III macroscopic patterns compared with 26% patients in the conformity group (p = 0.025). Univariate analyses demonstrated that ulcerative lesions (OR = 7.516, 95% Confidence Interval [CI] 2.574–21.952, p < 0.001), location at the cardia of the stomach (OR = 3.619, 95%CI 1.076–12.168, p = 0.038), malignant tumor (OR = 2.920, 95%CI 1.339–6.368, p = 0.007) were significantly associated with EUS inaccuracy. Multivariate logistic regression analyses showed that ulcer was an independent risk factor associated with EUS inaccuracy, with odds ratios of 5.094 (95% CI: 1.641–15.807, p = 0.005). Conclusions Our findings suggested that EUS is a reliable and easy‐to‐use diagnostic tool in decision‐making regarding appropriate endoscopic treatment for gastrointestinal tumors. However, the diagnostic accuracy of EUS appeared questionable in the presence of ulceration.https://doi.org/10.1002/cam4.5305diagnostic accuracyendoscopic submucosal dissectionendoscopic ultrasonographygastrointestinal superficial tumorspre‐operative assessments |
| spellingShingle | Yan Zhao Mudan Ren Ai Jia Juan Zhang Shuying Wang Qian Zhao Guohong Cai Shuixiang He The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors Cancer Medicine diagnostic accuracy endoscopic submucosal dissection endoscopic ultrasonography gastrointestinal superficial tumors pre‐operative assessments |
| title | The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| title_full | The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| title_fullStr | The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| title_full_unstemmed | The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| title_short | The factors influencing the accuracy of pre‐operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| title_sort | factors influencing the accuracy of pre operative endoscopic ultrasonography assessment in endoscopic treatments for gastrointestinal tumors |
| topic | diagnostic accuracy endoscopic submucosal dissection endoscopic ultrasonography gastrointestinal superficial tumors pre‐operative assessments |
| url | https://doi.org/10.1002/cam4.5305 |
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