Association between exposure to ambient air pollution and renal function in Korean adults
Abstract Background Ambient air pollution has a negative effect on many diseases, such as cardiovascular and respiratory diseases. Recent studies have reported a relationship between air pollution and renal function, but the results were limited to exposure to particulate matter (PM). This study was...
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| Format: | Article |
| Language: | English |
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Korean Society of Occupational & Environmental Medicine
2018-02-01
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| Series: | Annals of Occupational and Environmental Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40557-018-0226-z |
| _version_ | 1811180646809206784 |
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| author | Hyun-Jin Kim Jin-young Min Yong-Seok Seo Kyoung-bok Min |
| author_facet | Hyun-Jin Kim Jin-young Min Yong-Seok Seo Kyoung-bok Min |
| author_sort | Hyun-Jin Kim |
| collection | DOAJ |
| description | Abstract Background Ambient air pollution has a negative effect on many diseases, such as cardiovascular and respiratory diseases. Recent studies have reported a relationship between air pollution and renal function, but the results were limited to exposure to particulate matter (PM). This study was to identify associations between various air pollutants and renal function among Korean adults. Methods Nationwide survey data for a total of 24,407 adults were analyzed. We calculated the estimated glomerular filtration rate (eGFR) for each individual to assess their renal function and used this to categorize those with chronic kidney disease (CKD). To evaluate exposure to ambient air pollution, we used the annual mean concentrations of four ambient air pollutants: PM with an aerodynamic diameter ≤ 10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO). Results We identified significant inverse relationships between the air pollutants PM10 and NO2 and eGFR in all statistical adjustment models (all p < 0.05). In the full covariate model, interquartile range increases in the annual mean concentrations of PM10 and NO2 were associated with decreases in eGFR levels of 0.46 (95% CI = − 0.87, − 0.04) and 0.85 (95% CI = − 1.40, − 0.30), respectively. Three of the ambient air pollutants were significantly related to an increased risk of CKD in the unadjusted model (p < 0.0001), but all significant associations disappeared after adjusting for covariates (all p > 0.05). Conclusions Exposures to PM10 and NO2 were significantly associated with decreases in eGFR levels, but not CKD, in Korean adults. |
| first_indexed | 2024-04-11T09:05:38Z |
| format | Article |
| id | doaj.art-02a57a0366eb43c5930c1138bce6c2ae |
| institution | Directory Open Access Journal |
| issn | 2052-4374 |
| language | English |
| last_indexed | 2024-04-11T09:05:38Z |
| publishDate | 2018-02-01 |
| publisher | Korean Society of Occupational & Environmental Medicine |
| record_format | Article |
| series | Annals of Occupational and Environmental Medicine |
| spelling | doaj.art-02a57a0366eb43c5930c1138bce6c2ae2022-12-22T04:32:37ZengKorean Society of Occupational & Environmental MedicineAnnals of Occupational and Environmental Medicine2052-43742018-02-013011710.1186/s40557-018-0226-zAssociation between exposure to ambient air pollution and renal function in Korean adultsHyun-Jin Kim0Jin-young Min1Yong-Seok Seo2Kyoung-bok Min3Institute of Health and Environment, Seoul National UniversityInstitute of Health and Environment, Seoul National UniversityInstitute of Environmental Research, Kangwon National UniversityDepartment of Preventive Medicine, College of Medicine, Seoul National UniversityAbstract Background Ambient air pollution has a negative effect on many diseases, such as cardiovascular and respiratory diseases. Recent studies have reported a relationship between air pollution and renal function, but the results were limited to exposure to particulate matter (PM). This study was to identify associations between various air pollutants and renal function among Korean adults. Methods Nationwide survey data for a total of 24,407 adults were analyzed. We calculated the estimated glomerular filtration rate (eGFR) for each individual to assess their renal function and used this to categorize those with chronic kidney disease (CKD). To evaluate exposure to ambient air pollution, we used the annual mean concentrations of four ambient air pollutants: PM with an aerodynamic diameter ≤ 10 μm (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO). Results We identified significant inverse relationships between the air pollutants PM10 and NO2 and eGFR in all statistical adjustment models (all p < 0.05). In the full covariate model, interquartile range increases in the annual mean concentrations of PM10 and NO2 were associated with decreases in eGFR levels of 0.46 (95% CI = − 0.87, − 0.04) and 0.85 (95% CI = − 1.40, − 0.30), respectively. Three of the ambient air pollutants were significantly related to an increased risk of CKD in the unadjusted model (p < 0.0001), but all significant associations disappeared after adjusting for covariates (all p > 0.05). Conclusions Exposures to PM10 and NO2 were significantly associated with decreases in eGFR levels, but not CKD, in Korean adults.http://link.springer.com/article/10.1186/s40557-018-0226-zAmbient air pollutionAssociationRenal functionKorean adults |
| spellingShingle | Hyun-Jin Kim Jin-young Min Yong-Seok Seo Kyoung-bok Min Association between exposure to ambient air pollution and renal function in Korean adults Annals of Occupational and Environmental Medicine Ambient air pollution Association Renal function Korean adults |
| title | Association between exposure to ambient air pollution and renal function in Korean adults |
| title_full | Association between exposure to ambient air pollution and renal function in Korean adults |
| title_fullStr | Association between exposure to ambient air pollution and renal function in Korean adults |
| title_full_unstemmed | Association between exposure to ambient air pollution and renal function in Korean adults |
| title_short | Association between exposure to ambient air pollution and renal function in Korean adults |
| title_sort | association between exposure to ambient air pollution and renal function in korean adults |
| topic | Ambient air pollution Association Renal function Korean adults |
| url | http://link.springer.com/article/10.1186/s40557-018-0226-z |
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