Myocardial work: The analytical methodology and clinical utilities
The evaluation of left ventricular (LV) systolic function is an essential part of the clinical practice of cardiology. Although left ventricular ejection fraction (LVEF) is the most validated and widely used parameter, it has fundamental limitations. LV strain is more sensitive to detect subtle myoc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Hellenic Journal of Cardiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1109966622001142 |
| _version_ | 1811315626959962112 |
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| author | Xinhao Li Pengfei Zhang Mengmeng Li Mei Zhang |
| author_facet | Xinhao Li Pengfei Zhang Mengmeng Li Mei Zhang |
| author_sort | Xinhao Li |
| collection | DOAJ |
| description | The evaluation of left ventricular (LV) systolic function is an essential part of the clinical practice of cardiology. Although left ventricular ejection fraction (LVEF) is the most validated and widely used parameter, it has fundamental limitations. LV strain is more sensitive to detect subtle myocardial dysfunction when LVEF was preserved, but it is load-dependent. Invasive left ventricular pressure-volume loop (LV-PVL) is the reliable standard to evaluate cardiac function, but its wide clinical application is limited by the risk of invasive LV pressure detection. Until the advent of non-invasive LV pressure-strain loop (LV-PSL), things have changed. LV-PSL is in good agreement with regional myocardial oxygen consumption and metabolism. Compared with traditional echocardiographic parameters or LV strain, myocardial work (MW) derived from LV-PSL is a more advanced tool that combines deformation as well as hemodynamics through integration of global longitudinal strain and non-invasive LV systolic pressure. In recent years, researches on MW are going on in full swing and show many advantages of MW. This review described the method and discussed the applications, advantages, limitations, and prospects of MW in multiple cardiovascular diseases. The goal is to provide the readers new insights for evaluating LV systolic function and promote the incorporation of MW into daily practice. |
| first_indexed | 2024-04-13T11:33:38Z |
| format | Article |
| id | doaj.art-02a65e1f41864e09bef069197398f5de |
| institution | Directory Open Access Journal |
| issn | 1109-9666 |
| language | English |
| last_indexed | 2024-04-13T11:33:38Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hellenic Journal of Cardiology |
| spelling | doaj.art-02a65e1f41864e09bef069197398f5de2022-12-22T02:48:30ZengElsevierHellenic Journal of Cardiology1109-96662022-11-01684659Myocardial work: The analytical methodology and clinical utilitiesXinhao Li0Pengfei Zhang1Mengmeng Li2Mei Zhang3The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, ChinaThe Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, ChinaThe Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, ChinaCorresponding author. Mei Zhang, MD, Tel.: +8618560086629.; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Shandong, ChinaThe evaluation of left ventricular (LV) systolic function is an essential part of the clinical practice of cardiology. Although left ventricular ejection fraction (LVEF) is the most validated and widely used parameter, it has fundamental limitations. LV strain is more sensitive to detect subtle myocardial dysfunction when LVEF was preserved, but it is load-dependent. Invasive left ventricular pressure-volume loop (LV-PVL) is the reliable standard to evaluate cardiac function, but its wide clinical application is limited by the risk of invasive LV pressure detection. Until the advent of non-invasive LV pressure-strain loop (LV-PSL), things have changed. LV-PSL is in good agreement with regional myocardial oxygen consumption and metabolism. Compared with traditional echocardiographic parameters or LV strain, myocardial work (MW) derived from LV-PSL is a more advanced tool that combines deformation as well as hemodynamics through integration of global longitudinal strain and non-invasive LV systolic pressure. In recent years, researches on MW are going on in full swing and show many advantages of MW. This review described the method and discussed the applications, advantages, limitations, and prospects of MW in multiple cardiovascular diseases. The goal is to provide the readers new insights for evaluating LV systolic function and promote the incorporation of MW into daily practice.http://www.sciencedirect.com/science/article/pii/S1109966622001142systolic functionpressure-strain loopmyocardial workglobal longitudinal strainechocardiography |
| spellingShingle | Xinhao Li Pengfei Zhang Mengmeng Li Mei Zhang Myocardial work: The analytical methodology and clinical utilities Hellenic Journal of Cardiology systolic function pressure-strain loop myocardial work global longitudinal strain echocardiography |
| title | Myocardial work: The analytical methodology and clinical utilities |
| title_full | Myocardial work: The analytical methodology and clinical utilities |
| title_fullStr | Myocardial work: The analytical methodology and clinical utilities |
| title_full_unstemmed | Myocardial work: The analytical methodology and clinical utilities |
| title_short | Myocardial work: The analytical methodology and clinical utilities |
| title_sort | myocardial work the analytical methodology and clinical utilities |
| topic | systolic function pressure-strain loop myocardial work global longitudinal strain echocardiography |
| url | http://www.sciencedirect.com/science/article/pii/S1109966622001142 |
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