Sudden death associated with melanoma brain metastases

<p>A 48-year-old male Caucasian, with no relevant medical history except for a mild depression, was found by the partner, passed out on the bedroom floor. Since he was found in cardiac arrest, cardiopulmonary resuscitation was attempted, without success.  Initially, it was suspected to be a su...

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Main Authors: Durão H Carlos, Veiga G Marcos, Nina Pedro, Gonçalves M Manuela, Frederico Pedrosa
Format: Article
Language:English
Published: Association of Clinical Pathologists of Nepal 2018-09-01
Series:Journal of Pathology of Nepal
Subjects:
Online Access:https://www.nepjol.info/index.php/JPN/article/view/20896
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author Durão H Carlos
Veiga G Marcos
Nina Pedro
Gonçalves M Manuela
Frederico Pedrosa
author_facet Durão H Carlos
Veiga G Marcos
Nina Pedro
Gonçalves M Manuela
Frederico Pedrosa
author_sort Durão H Carlos
collection DOAJ
description <p>A 48-year-old male Caucasian, with no relevant medical history except for a mild depression, was found by the partner, passed out on the bedroom floor. Since he was found in cardiac arrest, cardiopulmonary resuscitation was attempted, without success.  Initially, it was suspected to be a suicide attempt and autopsy findings revealed coronary atherosclerosis of about 40%, with no other recoverable cardiac findings.</p><p>The brain showed multiple probable neoplastic lesions, associated with cerebral and cerebellar hemorrhage. The primary tumor was not identified, but the victim had multiple cutaneous nevi. Histological examination revealed melanoma metastases, confirmed by immunohistochemistry.</p><p>In this case, the forensic autopsy allowed an accurate determination of the cause of death. Besides having fulfilled its role to the judiciary system, the autopsy also had relevance from an epidemiological point of view, which is essential for Public Health prevention programs.</p><p> </p>
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spelling doaj.art-02a71dae67154de7a431002cefd5389e2022-12-21T19:17:37ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082018-09-01821412141510.3126/jpn.v8i2.2089616223Sudden death associated with melanoma brain metastasesDurão H CarlosVeiga G MarcosNina PedroGonçalves M ManuelaFrederico Pedrosa<p>A 48-year-old male Caucasian, with no relevant medical history except for a mild depression, was found by the partner, passed out on the bedroom floor. Since he was found in cardiac arrest, cardiopulmonary resuscitation was attempted, without success.  Initially, it was suspected to be a suicide attempt and autopsy findings revealed coronary atherosclerosis of about 40%, with no other recoverable cardiac findings.</p><p>The brain showed multiple probable neoplastic lesions, associated with cerebral and cerebellar hemorrhage. The primary tumor was not identified, but the victim had multiple cutaneous nevi. Histological examination revealed melanoma metastases, confirmed by immunohistochemistry.</p><p>In this case, the forensic autopsy allowed an accurate determination of the cause of death. Besides having fulfilled its role to the judiciary system, the autopsy also had relevance from an epidemiological point of view, which is essential for Public Health prevention programs.</p><p> </p>https://www.nepjol.info/index.php/JPN/article/view/20896BrainMelanomaMetastasis
spellingShingle Durão H Carlos
Veiga G Marcos
Nina Pedro
Gonçalves M Manuela
Frederico Pedrosa
Sudden death associated with melanoma brain metastases
Journal of Pathology of Nepal
Brain
Melanoma
Metastasis
title Sudden death associated with melanoma brain metastases
title_full Sudden death associated with melanoma brain metastases
title_fullStr Sudden death associated with melanoma brain metastases
title_full_unstemmed Sudden death associated with melanoma brain metastases
title_short Sudden death associated with melanoma brain metastases
title_sort sudden death associated with melanoma brain metastases
topic Brain
Melanoma
Metastasis
url https://www.nepjol.info/index.php/JPN/article/view/20896
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AT ninapedro suddendeathassociatedwithmelanomabrainmetastases
AT goncalvesmmanuela suddendeathassociatedwithmelanomabrainmetastases
AT fredericopedrosa suddendeathassociatedwithmelanomabrainmetastases