Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome
The aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Instituto Internacional de Ecologia
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| Series: | Brazilian Journal of Biology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842006000500020&lng=en&tlng=en |
| _version_ | 1818020953817350144 |
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| author | E. L. Ribeiro M. L. Scroferneker M. S. Cavalhaes C. C. Campos G. M. Nagato N. A. Souza W. M. Ferreira C. G. Cardoso S. M. S. Dias F. C. Pimenta O. A. Toledo |
| author_facet | E. L. Ribeiro M. L. Scroferneker M. S. Cavalhaes C. C. Campos G. M. Nagato N. A. Souza W. M. Ferreira C. G. Cardoso S. M. S. Dias F. C. Pimenta O. A. Toledo |
| author_sort | E. L. Ribeiro |
| collection | DOAJ |
| description | The aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth microdilution to determine the minimum inhibitory concentration (MIC). The morphotyping revealed that all oral C. albicans isolates from children with Down's syndrome promoted the formation of fringes regardless of size, while the control group presented smaller fringes. All oral C. albicans strains produced proteinase, but those with phospholipolytic activity showed greater enzyme capacity in the test group. In vitro susceptibility showed that all oral C. albicans isolates were sensitive to the drugs used. |
| first_indexed | 2024-04-14T08:12:23Z |
| format | Article |
| id | doaj.art-02acacdd7c9b4a7789e8aabc87b1234f |
| institution | Directory Open Access Journal |
| issn | 1678-4375 |
| language | English |
| last_indexed | 2024-04-14T08:12:23Z |
| publisher | Instituto Internacional de Ecologia |
| record_format | Article |
| series | Brazilian Journal of Biology |
| spelling | doaj.art-02acacdd7c9b4a7789e8aabc87b1234f2022-12-22T02:04:30ZengInstituto Internacional de EcologiaBrazilian Journal of Biology1678-437566393994410.1590/S1519-69842006000500020S1519-69842006000500020Phenotypic aspects of oral strains of Candida albicans in children with down's syndromeE. L. Ribeiro0M. L. Scroferneker1M. S. Cavalhaes2C. C. Campos3G. M. Nagato4N. A. Souza5W. M. Ferreira6C. G. Cardoso7S. M. S. Dias8F. C. Pimenta9O. A. Toledo10Universidade Federal de GoiásUniversidade Federal do Rio Grande do SulUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de GoiásThe aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth microdilution to determine the minimum inhibitory concentration (MIC). The morphotyping revealed that all oral C. albicans isolates from children with Down's syndrome promoted the formation of fringes regardless of size, while the control group presented smaller fringes. All oral C. albicans strains produced proteinase, but those with phospholipolytic activity showed greater enzyme capacity in the test group. In vitro susceptibility showed that all oral C. albicans isolates were sensitive to the drugs used.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842006000500020&lng=en&tlng=enPhenotypingCandida albicansDown's syndrome |
| spellingShingle | E. L. Ribeiro M. L. Scroferneker M. S. Cavalhaes C. C. Campos G. M. Nagato N. A. Souza W. M. Ferreira C. G. Cardoso S. M. S. Dias F. C. Pimenta O. A. Toledo Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome Brazilian Journal of Biology Phenotyping Candida albicans Down's syndrome |
| title | Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
| title_full | Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
| title_fullStr | Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
| title_full_unstemmed | Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
| title_short | Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
| title_sort | phenotypic aspects of oral strains of candida albicans in children with down s syndrome |
| topic | Phenotyping Candida albicans Down's syndrome |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842006000500020&lng=en&tlng=en |
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