Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma

Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-year-old man who presented with choroidal hem...

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Main Authors: Yewlin E. Chee, Raghu Mudumbai, Steven S. Saraf, Thellea Leveque, Verena S. Grieco, Monique A. Mogensen, Rebecca A. Yoda, Luis F. Gonzalez-Cuyar, Andrew W. Stacey
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993621001821
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author Yewlin E. Chee
Raghu Mudumbai
Steven S. Saraf
Thellea Leveque
Verena S. Grieco
Monique A. Mogensen
Rebecca A. Yoda
Luis F. Gonzalez-Cuyar
Andrew W. Stacey
author_facet Yewlin E. Chee
Raghu Mudumbai
Steven S. Saraf
Thellea Leveque
Verena S. Grieco
Monique A. Mogensen
Rebecca A. Yoda
Luis F. Gonzalez-Cuyar
Andrew W. Stacey
author_sort Yewlin E. Chee
collection DOAJ
description Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-year-old man who presented with choroidal hemorrhage and posterior scleritis. Vitrectomy with transvitreous fine needle aspiration biopsy was ultimately required to diagnose malignant uveal melanoma in each case. Conclusions and importance: Intraocular hemorrhage is a rare presenting sign of uveal melanoma. When it does occur, it is typically associated with large tumors. Hemorrhagic choroidal detachments are particularly rare in uveal melanoma, and can limit the diagnostic utility of clinical exam, B-scan ultrasonography, and magnetic resonance imaging. Although it is uncommon, it is important to maintain a high index of suspicion for choroidal melanoma in any patient with unexplained choroidal hemorrhage.
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spelling doaj.art-02ba6e9a720642a98766d3108ba4bfa42022-12-21T18:45:47ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-09-0123101173Hemorrhagic choroidal detachment as the presenting sign of uveal melanomaYewlin E. Chee0Raghu Mudumbai1Steven S. Saraf2Thellea Leveque3Verena S. Grieco4Monique A. Mogensen5Rebecca A. Yoda6Luis F. Gonzalez-Cuyar7Andrew W. Stacey8Department of Ophthalmology, University of Washington, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USADepartment of Pathology, Division of Cytology, University of Washington, Seattle, WA, USADepartment of Radiology, Division of Neuroradiology, University of Washington, Seattle, WA, USADepartment of Pathology, Division of Neuropathology, University of Washington, Seattle, WA, USADepartment of Pathology, Division of Neuropathology, University of Washington, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USA; Corresponding author. Department of Ophthalmology, University of Washington, 325 9th Ave, BOX 359608, Seattle, WA, 98104, USA.Purpose: To describe two cases of medium-sized uveal melanoma presenting with hemorrhagic choroidal detachments. Observations: The first case is a 39-year-old man who presented with choroidal hemorrhage and angle closure glaucoma. The second case is a 42-year-old man who presented with choroidal hemorrhage and posterior scleritis. Vitrectomy with transvitreous fine needle aspiration biopsy was ultimately required to diagnose malignant uveal melanoma in each case. Conclusions and importance: Intraocular hemorrhage is a rare presenting sign of uveal melanoma. When it does occur, it is typically associated with large tumors. Hemorrhagic choroidal detachments are particularly rare in uveal melanoma, and can limit the diagnostic utility of clinical exam, B-scan ultrasonography, and magnetic resonance imaging. Although it is uncommon, it is important to maintain a high index of suspicion for choroidal melanoma in any patient with unexplained choroidal hemorrhage.http://www.sciencedirect.com/science/article/pii/S2451993621001821Adult ocular oncologyChoroidal melanomaChoroidal hemorrhageRetinal and vitreous surgery
spellingShingle Yewlin E. Chee
Raghu Mudumbai
Steven S. Saraf
Thellea Leveque
Verena S. Grieco
Monique A. Mogensen
Rebecca A. Yoda
Luis F. Gonzalez-Cuyar
Andrew W. Stacey
Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
American Journal of Ophthalmology Case Reports
Adult ocular oncology
Choroidal melanoma
Choroidal hemorrhage
Retinal and vitreous surgery
title Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
title_full Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
title_fullStr Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
title_full_unstemmed Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
title_short Hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
title_sort hemorrhagic choroidal detachment as the presenting sign of uveal melanoma
topic Adult ocular oncology
Choroidal melanoma
Choroidal hemorrhage
Retinal and vitreous surgery
url http://www.sciencedirect.com/science/article/pii/S2451993621001821
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