Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome

The article presents the issues related to gut microbiota and short-chain fatty acids in patients with irritable bowel syndrome. It was found that the faecal concentration of acetic, propionic, butyric acids is higher in patients with irritable bowel syndrome with diarrhea, compared with the patient...

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Main Authors: Yu.M. Stepanov, I.Ya. Budzak, I.A. Klenina
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2019-09-01
Series:Gastroenterologìa
Subjects:
Online Access:http://gastro.zaslavsky.com.ua/article/view/181470
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author Yu.M. Stepanov
I.Ya. Budzak
I.A. Klenina
author_facet Yu.M. Stepanov
I.Ya. Budzak
I.A. Klenina
author_sort Yu.M. Stepanov
collection DOAJ
description The article presents the issues related to gut microbiota and short-chain fatty acids in patients with irritable bowel syndrome. It was found that the faecal concentration of acetic, propionic, butyric acids is higher in patients with irritable bowel syndrome with diarrhea, compared with the patients without diarrhea syndrome. 83.3–88.9% of patients with various forms of irritable bowel syndrome presented with dysbiotic changes. The reduced concentration of Bifidobacterium species, mainly lactic acid bacteria, is more often registered in patients with diarrheal form. There is a certain correlation between the concentration of short-chain fatty acids and the content of Bifidobacterium, Lactobacillus, Candida and opportunistic bacteria.
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spelling doaj.art-02ba7800e10d47f7a5742807ded66f362022-12-22T04:08:51ZengZaslavsky O.Yu.Gastroenterologìa2308-20972518-78802019-09-0153317818110.22141/2308-2097.53.3.2019.181470181470Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndromeYu.M. Stepanov0I.Ya. Budzak1I.A. Klenina2State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, UkraineState Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineState Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”, Dnipro, UkraineThe article presents the issues related to gut microbiota and short-chain fatty acids in patients with irritable bowel syndrome. It was found that the faecal concentration of acetic, propionic, butyric acids is higher in patients with irritable bowel syndrome with diarrhea, compared with the patients without diarrhea syndrome. 83.3–88.9% of patients with various forms of irritable bowel syndrome presented with dysbiotic changes. The reduced concentration of Bifidobacterium species, mainly lactic acid bacteria, is more often registered in patients with diarrheal form. There is a certain correlation between the concentration of short-chain fatty acids and the content of Bifidobacterium, Lactobacillus, Candida and opportunistic bacteria.http://gastro.zaslavsky.com.ua/article/view/181470irritable bowel syndromegut microbiotadysbiosisshort-chain fatty acids
spellingShingle Yu.M. Stepanov
I.Ya. Budzak
I.A. Klenina
Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
Gastroenterologìa
irritable bowel syndrome
gut microbiota
dysbiosis
short-chain fatty acids
title Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
title_full Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
title_fullStr Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
title_full_unstemmed Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
title_short Characteristics of the gut microbiota and the content of short-chain fatty acids in patients with irritable bowel syndrome
title_sort characteristics of the gut microbiota and the content of short chain fatty acids in patients with irritable bowel syndrome
topic irritable bowel syndrome
gut microbiota
dysbiosis
short-chain fatty acids
url http://gastro.zaslavsky.com.ua/article/view/181470
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AT iaklenina characteristicsofthegutmicrobiotaandthecontentofshortchainfattyacidsinpatientswithirritablebowelsyndrome