Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle
Using one carbon compounds as feedstock is a promising approach in abating climate change. Here, the authors report the conversion of E. coli into a synthetic methylotroph that assimilates methanol via the ribulose monophosphate cycle and a set of distinctive mutations.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32744-9 |
| _version_ | 1798003020193071104 |
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| author | Philipp Keller Michael A. Reiter Patrick Kiefer Thomas Gassler Lucas Hemmerle Philipp Christen Elad Noor Julia A. Vorholt |
| author_facet | Philipp Keller Michael A. Reiter Patrick Kiefer Thomas Gassler Lucas Hemmerle Philipp Christen Elad Noor Julia A. Vorholt |
| author_sort | Philipp Keller |
| collection | DOAJ |
| description | Using one carbon compounds as feedstock is a promising approach in abating climate change. Here, the authors report the conversion of E. coli into a synthetic methylotroph that assimilates methanol via the ribulose monophosphate cycle and a set of distinctive mutations. |
| first_indexed | 2024-04-11T12:01:26Z |
| format | Article |
| id | doaj.art-02bd1bac363e4f91a49fde6f68839b7f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T12:01:26Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-02bd1bac363e4f91a49fde6f68839b7f2022-12-22T04:24:50ZengNature PortfolioNature Communications2041-17232022-09-0113111310.1038/s41467-022-32744-9Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cyclePhilipp Keller0Michael A. Reiter1Patrick Kiefer2Thomas Gassler3Lucas Hemmerle4Philipp Christen5Elad Noor6Julia A. Vorholt7Institute of Microbiology, Department of Biology, ETH ZurichInstitute of Microbiology, Department of Biology, ETH ZurichInstitute of Microbiology, Department of Biology, ETH ZurichInstitute of Microbiology, Department of Biology, ETH ZurichInstitute of Microbiology, Department of Biology, ETH ZurichInstitute of Microbiology, Department of Biology, ETH ZurichDepartment of Plant and Environmental Sciences, Weizmann Institute of ScienceInstitute of Microbiology, Department of Biology, ETH ZurichUsing one carbon compounds as feedstock is a promising approach in abating climate change. Here, the authors report the conversion of E. coli into a synthetic methylotroph that assimilates methanol via the ribulose monophosphate cycle and a set of distinctive mutations.https://doi.org/10.1038/s41467-022-32744-9 |
| spellingShingle | Philipp Keller Michael A. Reiter Patrick Kiefer Thomas Gassler Lucas Hemmerle Philipp Christen Elad Noor Julia A. Vorholt Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle Nature Communications |
| title | Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| title_full | Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| title_fullStr | Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| title_full_unstemmed | Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| title_short | Generation of an Escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| title_sort | generation of an escherichia coli strain growing on methanol via the ribulose monophosphate cycle |
| url | https://doi.org/10.1038/s41467-022-32744-9 |
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