Integrative analysis of spatial transcriptome with single-cell transcriptome and single-cell epigenome in mouse lungs after immunization

Integrative analysis of spatial transcriptome with single-cell transcriptome and single-cell epigenome in mouse lungs after immunization

Summary: Understanding lung immunity requires an unbiased profiling of tissue-resident T cells at their precise anatomical locations within the lung, but such information has not been characterized in the immunized mouse model. In this pilot study, using 10x Genomics Chromium and Visium platform, we...

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Bibliographic Details
Main Authors: Zhongli Xu, Xinjun Wang, Li Fan, Fujing Wang, Becky Lin, Jiebiao Wang, Giraldina Trevejo-Nuñez, Wei Chen, Kong Chen
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Biological sciences
Immunology
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222011725

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