Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning
Cholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attem...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2020-06-01
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| Series: | Arhiv za Higijenu Rada i Toksikologiju |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/aiht-2020-71-3413 |
| _version_ | 1811272299889819648 |
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| author | Petreski Tadej Kit Barbara Strnad Matej Grenc Damjan Svenšek Franc |
| author_facet | Petreski Tadej Kit Barbara Strnad Matej Grenc Damjan Svenšek Franc |
| author_sort | Petreski Tadej |
| collection | DOAJ |
| description | Cholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attempted suicide by ingesting a purple crystal powder that turned out to be a mixture of carbofuran and chlormephos. At clinical examination, the patient presented with salivation, perspiration, diarrhoea, bradypnoea, loss of consciousness, and epileptic seizures. Laboratory tests showed low plasma cholinesterase, and we started obidoxime along with supportive intensive care treatment. He was later transferred to the psychiatry department for further diagnostics and treatment. |
| first_indexed | 2024-04-12T22:37:49Z |
| format | Article |
| id | doaj.art-02c2c37cb5e545e6aa7a9809e41422e8 |
| institution | Directory Open Access Journal |
| issn | 1848-6312 |
| language | English |
| last_indexed | 2024-04-12T22:37:49Z |
| publishDate | 2020-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Arhiv za Higijenu Rada i Toksikologiju |
| spelling | doaj.art-02c2c37cb5e545e6aa7a9809e41422e82022-12-22T03:13:48ZengSciendoArhiv za Higijenu Rada i Toksikologiju1848-63122020-06-0171216316610.2478/aiht-2020-71-3413Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoningPetreski Tadej0Kit Barbara1Strnad Matej2Grenc Damjan3Svenšek Franc4University Medical Centre Maribor, Clinic for Internal Medicine, Department of Nephrology, Maribor, SloveniaUniversity Medical Centre Maribor, Clinic for Internal Medicine, Intensive Care Unit, Maribor, SloveniaUniversity of Maribor, Faculty of Medicine, Maribor, SloveniaUniversity Medical Centre Ljubljana, Clinic for Internal Medicine, Centre for Clinical Toxicology and Pharmacology, Ljubljana, SloveniaUniversity Medical Centre Maribor, Clinic for Internal Medicine, Intensive Care Unit, Maribor, SloveniaCholinergic syndrome is a common topic at western medical universities yet rarely observed in clinical practice. The treatment involves muscarinic antagonists, acetylcholinesterase reactivation, seizure control, and supportive measures. Here we report a case of a 52-year old Caucasian male who attempted suicide by ingesting a purple crystal powder that turned out to be a mixture of carbofuran and chlormephos. At clinical examination, the patient presented with salivation, perspiration, diarrhoea, bradypnoea, loss of consciousness, and epileptic seizures. Laboratory tests showed low plasma cholinesterase, and we started obidoxime along with supportive intensive care treatment. He was later transferred to the psychiatry department for further diagnostics and treatment.https://doi.org/10.2478/aiht-2020-71-3413carbofuranchlormephoscritical careobidoximekarbofuranklormefosintenzivna medicinaobidoksim |
| spellingShingle | Petreski Tadej Kit Barbara Strnad Matej Grenc Damjan Svenšek Franc Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning Arhiv za Higijenu Rada i Toksikologiju carbofuran chlormephos critical care obidoxime karbofuran klormefos intenzivna medicina obidoksim |
| title | Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning |
| title_full | Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning |
| title_fullStr | Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning |
| title_full_unstemmed | Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning |
| title_short | Cholinergic syndrome: a case report of acute organophosphate and carbamate poisoning |
| title_sort | cholinergic syndrome a case report of acute organophosphate and carbamate poisoning |
| topic | carbofuran chlormephos critical care obidoxime karbofuran klormefos intenzivna medicina obidoksim |
| url | https://doi.org/10.2478/aiht-2020-71-3413 |
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