SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis

SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis

The bacterial species Streptomyces avermitilis is an important industrial producer of avermectins, which are widely utilized as effective anthelmintic and insecticidal drugs. We used gene deletion, complementation, and overexpression experiments to identify SAV4189, a MarR-family transcriptional reg...

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Bibliographic Details
Main Authors: Jia Guo, Xuan Zhang, Xiaorui Lu, Wenshuai Liu, Zhi Chen, Jilun Li, Linhong Deng, Ying Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Streptomyces avermitilis
avermectins
MarR-family regulator
SAV4189
sav_4190
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01358/full

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