A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

Abstract Background Systemic sclerosis (SSc) is a disorder characterized by immune system alterations, vasculopathy and fibrosis. SSc-related interstitial lung disease (ILD) represents a common and early complication, being the leading cause of mortality. Monocytes/macrophages seem to have a key rol...

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Bibliographic Details
Main Authors: Amelia Chiara Trombetta, Stefano Soldano, Paola Contini, Veronica Tomatis, Barbara Ruaro, Sabrina Paolino, Renata Brizzolara, Paola Montagna, Alberto Sulli, Carmen Pizzorni, Vanessa Smith, Maurizio Cutolo
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Respiratory Research
Subjects:
Systemic sclerosis
Interstitial lung disease
Pulmonary artery hypertension
Monocyte/macrophage phenotype
M1
M2
Online Access:http://link.springer.com/article/10.1186/s12931-018-0891-z

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