Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases

Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...

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Manylion Llyfryddiaeth
Prif Awduron: Min Kyung Sung, Hyoeun Bang, Jung Kyoon Choi
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BioMed Central 2014-12-01
Cyfres:Genomics & Informatics
Pynciau:
Mynediad Ar-lein:http://genominfo.org/upload/pdf/gni-12-181.pdf