An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes

An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes

Abstract Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining control of VL in terms of proper and prevailing immunity development is a global necessity amid unavailability of a prop...

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Bibliographic Details
Main Authors: Md Anik Ashfaq Khan, Jenifar Quaiyum Ami, Khaledul Faisal, Rajashree Chowdhury, Prakash Ghosh, Faria Hossain, Ahmed Abd El Wahed, Dinesh Mondal
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Parasites & Vectors
Subjects:
Visceral leishmaniasis
In silico vaccine design
Reverse vaccinology using proteomics
Online Access:http://link.springer.com/article/10.1186/s13071-020-04064-8

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