Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases
Abstract Background Solitary adrenal metastasis from colorectal cancer is rare. Adrenal metastasis is usually detected with synchronous multiple metastases in other organs and is, therefore, considered to be unsuitable for surgical resection. The long-term outcomes of patients with solitary adrenal...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-04-01
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| Series: | Surgical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s40792-019-0611-z |
| _version_ | 1819074838680043520 |
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| author | Akinori Tsujimoto Takeshi Ueda Hiroyuki Kuge Takashi Inoue Shinsaku Obara Takayuki Nakamoto Yoshiyuki Sasaki Yasuyuki Nakamura Fumikazu Koyama Masayuki Sho |
| author_facet | Akinori Tsujimoto Takeshi Ueda Hiroyuki Kuge Takashi Inoue Shinsaku Obara Takayuki Nakamoto Yoshiyuki Sasaki Yasuyuki Nakamura Fumikazu Koyama Masayuki Sho |
| author_sort | Akinori Tsujimoto |
| collection | DOAJ |
| description | Abstract Background Solitary adrenal metastasis from colorectal cancer is rare. Adrenal metastasis is usually detected with synchronous multiple metastases in other organs and is, therefore, considered to be unsuitable for surgical resection. The long-term outcomes of patients with solitary adrenal metastasectomy from colorectal cancer have been reported; however, the survival advantage has not been established. We herein report two cases of curative adrenal resection in patients with solitary adrenal metastasis from colorectal cancer who achieved long-term survival of > 9 years without recurrence after surgical resection. Case presentation The first case involved a 71-year-old man who underwent abdominoperineal rectal resection for rectal cancer. Preoperative CT revealed a mass in the right adrenal, which was growing after surgery. After chemotherapy the adrenal mass decreased in size, and adrenalectomy was performed at 8 months after the first surgery. A pathological examination confirmed metastasis from rectal cancer. The patient received adjuvant chemotherapy and is currently alive without recurrence at 9 years after the adrenalectomy. The second case involved a 53-year-old man who underwent sigmoidectomy for sigmoid colon cancer. Four years later, lobectomy was performed for isolated lung metastasis. Twenty months later, PET-CT revealed solitary metastasis in the left adrenal gland and adrenalectomy was performed. A histopathological examination revealed metastatic adenocarcinoma of sigmoid cancer. Postoperative chemotherapy was administered after adrenalectomy and the patient is currently alive and apparently disease-free at more than 9 years after undergoing adrenal metastasectomy. Conclusion Curative resection for solitary adrenal metastasis from colorectal cancer may be beneficial for survival. |
| first_indexed | 2024-12-21T18:15:53Z |
| format | Article |
| id | doaj.art-02cb1ad528c544799abab56547a9524b |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-21T18:15:53Z |
| publishDate | 2019-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-02cb1ad528c544799abab56547a9524b2022-12-21T18:54:39ZengSpringerOpenSurgical Case Reports2198-77932019-04-01511610.1186/s40792-019-0611-zLong-term survival after adrenal metastasectomy from colorectal cancer: a report of two casesAkinori Tsujimoto0Takeshi Ueda1Hiroyuki Kuge2Takashi Inoue3Shinsaku Obara4Takayuki Nakamoto5Yoshiyuki Sasaki6Yasuyuki Nakamura7Fumikazu Koyama8Masayuki Sho9Department of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityDepartment of Surgery, Nara Medical UniversityAbstract Background Solitary adrenal metastasis from colorectal cancer is rare. Adrenal metastasis is usually detected with synchronous multiple metastases in other organs and is, therefore, considered to be unsuitable for surgical resection. The long-term outcomes of patients with solitary adrenal metastasectomy from colorectal cancer have been reported; however, the survival advantage has not been established. We herein report two cases of curative adrenal resection in patients with solitary adrenal metastasis from colorectal cancer who achieved long-term survival of > 9 years without recurrence after surgical resection. Case presentation The first case involved a 71-year-old man who underwent abdominoperineal rectal resection for rectal cancer. Preoperative CT revealed a mass in the right adrenal, which was growing after surgery. After chemotherapy the adrenal mass decreased in size, and adrenalectomy was performed at 8 months after the first surgery. A pathological examination confirmed metastasis from rectal cancer. The patient received adjuvant chemotherapy and is currently alive without recurrence at 9 years after the adrenalectomy. The second case involved a 53-year-old man who underwent sigmoidectomy for sigmoid colon cancer. Four years later, lobectomy was performed for isolated lung metastasis. Twenty months later, PET-CT revealed solitary metastasis in the left adrenal gland and adrenalectomy was performed. A histopathological examination revealed metastatic adenocarcinoma of sigmoid cancer. Postoperative chemotherapy was administered after adrenalectomy and the patient is currently alive and apparently disease-free at more than 9 years after undergoing adrenal metastasectomy. Conclusion Curative resection for solitary adrenal metastasis from colorectal cancer may be beneficial for survival.http://link.springer.com/article/10.1186/s40792-019-0611-zColorectal cancerAdrenal metastasisAdrenalectomyLong-term survival |
| spellingShingle | Akinori Tsujimoto Takeshi Ueda Hiroyuki Kuge Takashi Inoue Shinsaku Obara Takayuki Nakamoto Yoshiyuki Sasaki Yasuyuki Nakamura Fumikazu Koyama Masayuki Sho Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases Surgical Case Reports Colorectal cancer Adrenal metastasis Adrenalectomy Long-term survival |
| title | Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases |
| title_full | Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases |
| title_fullStr | Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases |
| title_full_unstemmed | Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases |
| title_short | Long-term survival after adrenal metastasectomy from colorectal cancer: a report of two cases |
| title_sort | long term survival after adrenal metastasectomy from colorectal cancer a report of two cases |
| topic | Colorectal cancer Adrenal metastasis Adrenalectomy Long-term survival |
| url | http://link.springer.com/article/10.1186/s40792-019-0611-z |
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