New combined topical therapy for refractory rosacea

The main pathogenetic aspects of rosacea, various classifications of dermatosis and the modern clinical classification are presented. The symptoms of different forms of rosacea are described. Contradictory of modern scientific concepts of different researchers, approaches to etiology, pathogenesis a...

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Bibliographic Details
Main Authors: E. A. Smirnova, O. Yu. Olisova, N. G. Kochergin
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2018-12-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://www.vestnikdv.ru/jour/article/view/420
Description
Summary:The main pathogenetic aspects of rosacea, various classifications of dermatosis and the modern clinical classification are presented. The symptoms of different forms of rosacea are described. Contradictory of modern scientific concepts of different researchers, approaches to etiology, pathogenesis and treatment has been noted. The main triggers for the manifestation of rosacea, which should be tak en into account to achieve the maximum effect in the treatment of the disease, are indicated. The first domestic positive experience of authors with 1 % ivermectin cream and 0.03 % tacrolimus ointment is presented. The high efficacy and very good tolerability of this combination, compared to monotherapy of 1 % ivermectin cream and traditional therapy of metronidazole cream and azelaic acid gel as well as the absence of any side effects in patients with moderate to severe rosacea are shown.
ISSN:0042-4609
2313-6294