Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure
Background: For patients with chronic respiratory failure (CRF) who are treated with noninvasive positive pressure ventilation (NPPV), a little is known regarding the effects of low-intensity NPPV (LI-NPPV) on the clinical course of CRF and the frequency of adjustments in these patients. Objectives:...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Annals of Thoracic Medicine |
| Subjects: | |
| Online Access: | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2016;volume=11;issue=2;spage=141;epage=145;aulast=Kadowaki |
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| author | Toru Kadowaki Kiryo Wakabayashi Masahiro Kimura Kanako Kobayashi Toshikazu Ikeda Shuichi Yano |
| author_facet | Toru Kadowaki Kiryo Wakabayashi Masahiro Kimura Kanako Kobayashi Toshikazu Ikeda Shuichi Yano |
| author_sort | Toru Kadowaki |
| collection | DOAJ |
| description | Background: For patients with chronic respiratory failure (CRF) who are treated with noninvasive positive pressure ventilation (NPPV), a little is known regarding the effects of low-intensity NPPV (LI-NPPV) on the clinical course of CRF and the frequency of adjustments in these patients.
Objectives: This study investigated the effects of LI-NPPV on the clinical course of patients with CRF as compared with patients who were treated with conventional NPPV (C-NPPV) and determined how frequently NPPV was adjusted during therapy.
Methods: Clinical data from 21 patients who received long-term NPPV were retrospectively analyzed. Patients were categorized into two groups based on the level of initial pressure support (PS): C-NPPV group (PS ≥ 10 cm H2O) and LI-NPPV group (PS < 10 cm H2O).
Results: Patients in the LI-NPPV group had significantly more exacerbations of CRF (P < 0.05). There was no significant difference in the number of patients who required adjustments of NPPV settings between the two groups. There was no significant difference in PaCO2levels 1 month after the start of NPPV between the two groups; however, PaCO2levels were significantly lower after 1 year in the C-group (P < 0.001). Seventy-one percent of LI-NPPV patients and 43% of C-NPPV patients needed NPPV adjustments.
Conclusions: Attention should be paid to CRF patients who are initially administered LI-NPPV; they should be carefully observed because they can develop more exacerbations of CRF than patients undergoing C-NPPV. If possible, higher initial PS should be administered to prevent CRF exacerbations. |
| first_indexed | 2024-04-13T02:47:19Z |
| format | Article |
| id | doaj.art-02d087cad0794fff936ebca1fb4f3591 |
| institution | Directory Open Access Journal |
| issn | 1817-1737 1998-3557 |
| language | English |
| last_indexed | 2024-04-13T02:47:19Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Thoracic Medicine |
| spelling | doaj.art-02d087cad0794fff936ebca1fb4f35912022-12-22T03:05:58ZengWolters Kluwer Medknow PublicationsAnnals of Thoracic Medicine1817-17371998-35572016-01-0111214114510.4103/1817-1737.180029Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failureToru KadowakiKiryo WakabayashiMasahiro KimuraKanako KobayashiToshikazu IkedaShuichi YanoBackground: For patients with chronic respiratory failure (CRF) who are treated with noninvasive positive pressure ventilation (NPPV), a little is known regarding the effects of low-intensity NPPV (LI-NPPV) on the clinical course of CRF and the frequency of adjustments in these patients. Objectives: This study investigated the effects of LI-NPPV on the clinical course of patients with CRF as compared with patients who were treated with conventional NPPV (C-NPPV) and determined how frequently NPPV was adjusted during therapy. Methods: Clinical data from 21 patients who received long-term NPPV were retrospectively analyzed. Patients were categorized into two groups based on the level of initial pressure support (PS): C-NPPV group (PS ≥ 10 cm H2O) and LI-NPPV group (PS < 10 cm H2O). Results: Patients in the LI-NPPV group had significantly more exacerbations of CRF (P < 0.05). There was no significant difference in the number of patients who required adjustments of NPPV settings between the two groups. There was no significant difference in PaCO2levels 1 month after the start of NPPV between the two groups; however, PaCO2levels were significantly lower after 1 year in the C-group (P < 0.001). Seventy-one percent of LI-NPPV patients and 43% of C-NPPV patients needed NPPV adjustments. Conclusions: Attention should be paid to CRF patients who are initially administered LI-NPPV; they should be carefully observed because they can develop more exacerbations of CRF than patients undergoing C-NPPV. If possible, higher initial PS should be administered to prevent CRF exacerbations.http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2016;volume=11;issue=2;spage=141;epage=145;aulast=KadowakiAdjustmentchronic respiratory failureexacerbationlow-intensity noninvasive positive pressure ventilationnoninvasive positive pressure ventilation |
| spellingShingle | Toru Kadowaki Kiryo Wakabayashi Masahiro Kimura Kanako Kobayashi Toshikazu Ikeda Shuichi Yano Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure Annals of Thoracic Medicine Adjustment chronic respiratory failure exacerbation low-intensity noninvasive positive pressure ventilation noninvasive positive pressure ventilation |
| title | Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure |
| title_full | Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure |
| title_fullStr | Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure |
| title_full_unstemmed | Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure |
| title_short | Low-intensity noninvasive ventilation: Lower pressure, more exacerbations of chronic respiratory failure |
| title_sort | low intensity noninvasive ventilation lower pressure more exacerbations of chronic respiratory failure |
| topic | Adjustment chronic respiratory failure exacerbation low-intensity noninvasive positive pressure ventilation noninvasive positive pressure ventilation |
| url | http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2016;volume=11;issue=2;spage=141;epage=145;aulast=Kadowaki |
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