Single-cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks involved In the Central Circadian Clock

Single-cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks involved In the Central Circadian Clock

Single-cell heterogeneity confounds efforts to understand how a population of cells organizes into cellular networks that underlie tissue-level function. This complexity is prominent in the mammalian suprachiasmatic nucleus (SCN). Here, individual neurons exhibit a remarkable amount of asynchronous...

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Bibliographic Details
Main Authors: James Park, Haisun Zhu, Sean O'Sullivan, Babatunde Ogunnaike, David Weaver, James Schwaber, Rajanikanth Vadigepalli
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Neuroscience
Subjects:
network topology
Transcriptional heterogeneity
Single-cells
Cell-network
transcriptional phenotypes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00481/full

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